Protein Alignment Eaat1 and slc1a1

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_002934228.2
• Gene: slc1a1 / 100498100
• XenbaseID: XB-GENE-1011544
• Length: 529
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 219/485 - (45%)
• Similarity: 311/485 - (64%)
• Gaps: 34/485 - (7%)

  Fly     1 MTRPKQDGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLK 65
            |.:..:.|...|..::.|.|.:.|::.|.:|..:|.::: ..|:.|..:.:|.:|||||.:||||
 Frog     1 MGKKMKRGCDCKRILKNNWLLITTIVAVVLGIGLGVLVR-EYGKLSNLDKIYFAFPGEILMRMLK 64

  Fly    66 CLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT 130
            .:|:||:|||:.:.:..||.|:|.||..|||.|||.||:.||||||.||.:::||     |....
 Frog    65 LIILPLIVSSMITGVAALDSSVSGKIGLRAIVYYFCTTVIAVILGIVLVVSIKPG-----VSQSA 124

  Fly   131 ESIDKAS---KVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYE---------------NTSISP 177
            :.||:..   :|.|.|.|:||:||||.:|::|:...|::|:..|               |.:|..
 Frog   125 DEIDRTGSTPEVTTVDALLDLLRNMFPENLVQACFQQYKTKREELKPSKEPDKNSTVEGNYTIDL 189

  Fly   178 A------QPMENWEFK--SAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTI 234
            |      |..::.|:|  ....:|.|||||::|.::.|..||:|.||||:|.|||..|::|.|.|
 Frog   190 ALLALADQQNKSKEYKIVGLYTDGVNVLGLIVFCLVFGIVIGKMGEKGQVLVDFFNALNDATMQI 254

  Fly   235 TSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPY 299
            ...::|..|:|:.||||.||||:.. ....:.||.|..||:.||.:|....:.:|:.:..|:.|:
 Frog   255 VQIIMWYMPVGILFLIAGKIIEVND-WEIFRKLGLYMATVLSGLAIHSIVILPLIYLIIVRKNPF 318

  Fly   300 RYIAKLSQVLATAFGTGSSSATMPLTIKCLDNMG-IDPRVTRFVIPVGATINMDGTALYEAVAAL 363
            |:...::|.|.||....|||||:|:|.:|.:... :|.|:||||:|||||||||||||||||||:
 Frog   319 RFAMGMAQALLTALMISSSSATLPVTFRCAEEKNRVDKRITRFVLPVGATINMDGTALYEAVAAV 383

  Fly   364 FIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLD 428
            ||||..:|:...|.||.:|:||||||:||||:|||||||||:||..|||..:||:||||||||||
 Frog   384 FIAQLNDMNLDVGQIVTISVTATAASVGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLD 448

  Fly   429 RFRTTINVMCDALGTILVNHLSKNDLASVD 458
            ||||.:||:.||.||.:|..|||.:|..:|
 Frog   449 RFRTMVNVLGDAFGTGIVEKLSKRELELMD 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	210/455 (46%)
slc1a1	XP_002934228.2	SDF	20..469	CDD:395299	210/455 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	391	1.000	Domainoid score	I776
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	405	1.000	Inparanoid score	I1853
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm49148
Panther	1	1.100	-	-	LDO	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.080