Protein Alignment Eaat1 and slc1a2

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_004913402.1
• Gene: slc1a2 / 100494868
• XenbaseID: XB-GENE-1005169
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 211/545 - (38%)
• Similarity: 323/545 - (59%)
• Gaps: 47/545 - (8%)

  Fly     2 TRPKQDGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKC 66
            |||:....:....::.|:|...||.||.:|.:.|.:::.:: ......:|.|:|||:|.:||||.
 Frog    32 TRPRSPCLRICDKIRGNLLLSLTVFGVIMGAVSGGLLRMAS-PIHPDIVMVIAFPGDILMRMLKM 95

  Fly    67 LIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTE 131
            ||:||::||:.:.:.|||...|.::.|||:.||..|||.|.|||:.||..:.||...  ::.|..
 Frog    96 LILPLIISSLITGLAGLDAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPK--LKKQLG 158

  Fly   132 SIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQPMEN------------- 183
            ...:..:|.:.|..:||:||:|.:|::|:...|.:|...:....:|.:...|
 Frog   159 KGQENDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVVVEAPTEEPSNVTDSVFALMNDTV 223

  Fly   184 ----------WEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWV 238
                      .|||    :|.||||::.|.:..|..:|:|.|:.:|:.:||..|:|.:|.:.:.:
 Frog   224 ATTTEEIRKKLEFK----DGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMI 284

  Fly   239 IWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIA 303
            :|.||||:|.||..|||.::.:....:.||.|.:||::||.:||...:.:::|:.||:.|:.::|
 Frog   285 MWYSPLGIACLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLA 349

  Fly   304 KLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQ 367
            .:.|...||.||.||:.|:|:|.:|| :|:|||.||||||:|||||||||||||||||||:||||
 Frog   350 GVFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQ 414

  Fly   368 YREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRT 432
            ...:....|.|:.||:|||.||:|||.||.||||||:::|..|||..:|:||::||||||||.||
 Frog   415 MNGVILDGGQIITVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRT 479

  Fly   433 TINVMCDALGTILVNHLSKNDLASVDRLNAEPHELLEL--------GPNGHEMKEXRQSSLGAYN 489
            ::||:.|:.|..:|.||||.:|.|:|:.:|  |:.:|:        ....|......|....|:|
 Frog   480 SVNVVGDSFGAGIVYHLSKAELESLDKQHA--HQEIEMTKTQSIYDDMKNHRENNSNQCIYAAHN 542

  Fly   490 RKRXVDMSRLWACFHILPSNDSDSD 514
            .....|      |...|.:|...:|
 Frog   543 SVPVDD------CKVTLANNGKTAD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	188/452 (42%)
slc1a2	XP_004913402.1	SDF	50..496	CDD:366058	188/452 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	1	1.000	-	-		otm49148
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X191
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010