Protein Alignment Eaat1 and slc1a4

DIOPT Version :9

• Sequence 1: NP_001369123.1
• Gene: Eaat1 / 34251
• FlyBaseID: FBgn0026439
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001096391.1
• Gene: slc1a4 / 100124992
• XenbaseID: XB-GENE-980499
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 184/509 - (36%)
• Similarity: 304/509 - (59%)
• Gaps: 34/509 - (6%)

  Fly     4 PKQ----DGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRML 64
            ||:    :|.:...|:::|.:.:.||.||.||..:|..::..  ..:|.::.|.:||||:.||||
 Frog    32 PKKKKAAEGHRCAQFLKKNAIVILTVSGVLVGVGLGTAVRKM--NLTKAQMSYFAFPGEMLLRML 94

  Fly    65 KCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQ 129
            |.:|:||:|.|:.|....||.....|:...|:.|:.|||:.|..|.|.|...::||.||..:.:.
 Frog    95 KMIILPLVVCSLISGAASLDTRSLGKLGGIAVAYFLVTTLMASGLAIALGFIIKPGAGAGALNSN 159

  Fly   130 TESIDKA--SKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTE---IYENTS---ISPAQPMENWEF 186
            ...|::|  :...|.|:.:||.||:...|::.:......|:   ..:||:   |:...|:
 Frog   160 ELGIEEALSTNKETVDSFLDLARNLMPSNLVAAAFRSFATDYKTFTKNTTDGLITEKVPI----- 219

  Fly   187 KSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIA 251
             ..:.||.|:||||:|:::||..:.::..:|:.|..||...:||.|.:.||::|..|:|:.||:.
 Frog   220 -GTEVEGMNILGLVLFALVLGVALKKLGPEGEELIRFFNAFNEATMVLVSWIMWYVPIGIMFLVG 283

  Fly   252 AKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTG 316
            :||:||.:|...:.|||.|.:..::|..:||...:.:|:|..||:.||.::..|....||||.|.
 Frog   284 SKIVEMGNIVLLVTSLGKYIMASILGHVIHGGIVLPLIYFAFTRKNPYTFLLGLITPFATAFATS 348

  Fly   317 SSSATMPLTIKCL-DNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVA 380
            |||||:|..|||: :|.|:|.|::||::|:|||:||||.|:::.:||:||||......:.|.|..
 Frog   349 SSSATLPTMIKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCMAAVFIAQMNSAELNAGQIFT 413

  Fly   381 VSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTIL 445
            :.:||||:|:||||||..|::|:.::|:.:||...|:|||:||||::||..|.:||..||||..:
 Frog   414 ILVTATASSVGAAGIPAGGVLTIAIILEAIGLPTNDLSLILAVDWIVDRTTTVVNVEGDALGAGI 478

  Fly   446 VNHLSKNDLASVDRLNAEPHEL----LELGPNGHEMKEXRQSSLGAYNRKRXVD 495
            ::||::.:.|.      :.:||    :|..||   :|...::|....:|:...|
 Frog   479 LHHLNQKESAK------KQYELTDVYVEAVPN---LKSEEETSPLVMHRENPSD 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eaat1	NP_001369123.1	SDF	20..449	CDD:395299	167/437 (38%)
slc1a4	NP_001096391.1	SDF	52..482	CDD:278787	167/437 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	391	1.000	Domainoid score	I776
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62336
OrthoDB	1	1.010	-	-		D1184392at2759
OrthoFinder	1	1.000	-	-		FOG0000144
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030