| Sequence 1: | NP_609278.1 | Gene: | aust / 34244 | FlyBaseID: | FBgn0032104 | Length: | 216 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_080836.3 | Gene: | Cdca8 / 52276 | MGIID: | 1196274 | Length: | 289 | Species: | Mus musculus |
| Alignment Length: | 270 | Identity: | 57/270 - (21%) |
|---|---|---|---|
| Similarity: | 90/270 - (33%) | Gaps: | 100/270 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 DREEKVRLSQIKMDSALEKIDEMSKRYKQEVDNQIKVIRGRTDKQLLQMKMPEFLALG------- 75
Fly 76 --------------------------------------------------------FKTFAEFQR 84
Fly 85 AAIK---PPTTRSLSI-SRGRTR-------TP-QNALPPRLQAHSVDRALSGDTMSF----VRWP 133
Fly 134 RAGEMV--LSKAGSPLAVQMRPDRYADVHIPTRGGVITVKPHKI--NTVKREVLMQLDENTLNQV 194
Fly 195 KTLNANLGLI 204 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| aust | NP_609278.1 | Borealin | 96..207 | CDD:463127 | 33/126 (26%) |
| Cdca8 | NP_080836.3 | Required for interaction with SENP3. /evidence=ECO:0000250 | 1..150 | 20/129 (16%) | |
| Required for centromere localization. /evidence=ECO:0000250 | 1..88 | 19/67 (28%) | |||
| Required for interaction with INCENP. /evidence=ECO:0000250 | 1..58 | 11/37 (30%) | |||
| Required to form a minimal CPC core complex that localizes to the central spindle and midbody and properly executes the role of the CPC during cytokinesis. /evidence=ECO:0000250 | 10..109 | 19/88 (22%) | |||
| Required for interaction with INCENP and BIRC5. /evidence=ECO:0000250 | 20..78 | 18/57 (32%) | |||
| Nbl1_Borealin_N | 20..76 | CDD:463095 | 16/55 (29%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 122..173 | 10/50 (20%) | |||
| Borealin | 170..284 | CDD:463127 | 29/120 (24%) |