|
Fly 242 NNEKRRREAENGYIEQLSEILTLNKRG-DMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTST 305
:.||||||.||.|:|:|:|:|:.|... |..|.||||..||.:.| |......
Mouse 30 STEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTV-------------DQIQLMK 81
Fly 306 NNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPE-----PS 365
......:||::: ||:.::||:...:.| |.
Mouse 82 RMEQEKSTTDDD-------------------------------VQKSDISSSSQGVIEKESLGPL 115
Fly 366 LLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYS 430
|| |||:.: ...||..|.|...::|:...:||.::||.:..:|..|:.
Mouse 116 LL-----------EALDGF-------FFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHV 162
Fly 431 GDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGL 495
|||| |.:.|.: ..|..|..| |..
Mouse 163 GDHA--EFVKNLL--------PKSLVNGVP-----------WPQ--------------------- 185
Fly 496 GGAGGAAAGKKRSISTKVRMLV---KDTRTATQTSSNCEEKPLRQSGHQDKYE--EVVLIAAP-- 553
.|.::.|.:...|||: :|..|..|.: |: :|| :...::.|
Mouse 186 ------EATRRNSHTFNCRMLIHPPEDPGTENQEA--CQ-----------RYEVMQCFTVSQPKS 231
Fly 554 VKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQH 618
:::|.:...|.|..|.|.....|....::..:.:| |..|||:::|.::||.
Mouse 232 IQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQ---------DTTGKIISIDTSSLRA----- 282
Fly 619 LQTWVGRL-WQDLCHP----------HDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRL 672
.||. |:||... .:.|..:...:::....:|:|| |..|.|..
Mouse 283 ----AGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSP---------SYRFILND 334
Fly 673 GAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTL------LNSENDMNSS----------NTGAGS 721
|.. :..|.|. :|...|:|....|||.:..: |:.::|.||. |.|. |
Mouse 335 GTM-LSAHTKC--KLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGI-S 395
Fly 722 GGLGLGQLCAMAPS-PSLASSLLSSLSMDGLHGGTG-SGSSSSPAASGMLPTHLLGGLVGGGQ-- 782
...|:.:...:.|| .::.|:.::......|:..:. :.||::....|..| |.|
Mouse 396 PAHGVTRSSTLPPSNNNMVSARVNRQQSSDLNSSSSHTNSSNNQGNFGCSP---------GNQIV 451
Fly 783 ------QGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASP 841
||..|:.:...|:. ::::.:.|||:...|....|..|:|..::.|....|:|..:
Mouse 452 ANVALNQGQAGSQSSNPSLN---LNNSPMEGTGIALSQFMSPRRQANSGLATRARMSNNSFPPN- 512
Fly 842 APAEHSFYGSDTFEFDIAAHSSSFELDPSGGVGAWTDSRPNSRASVATPVSTPR-----PPSGHG 901
.|...|..|..: ||..: |:|:....||::.: |.:..|
Mouse 513 IPTLSSPVGITS--------------------GACNN---NNRSYSNIPVTSLQGMNEGPNNSVG 554
Fly 902 FSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQ-Q 965
|| ..||......|.:|.:.|....:.|.: |..|::....|:. |
Mouse 555 FS---AGSPVLRQMSSQNSPSRLSMQPAKAES------------------KDSKEIASILNEMIQ 598
Fly 966 SNNNSSSSN---PLLGGGLPN----GVGGMLLSQQQQQ--QQTPPQQQQQQQQQESSERLRHLL- 1020
|:|:.:|:| ||..|.|.| ..|....||...: |......:||.:..:.....:.:|
Mouse 599 SDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLS 663
Fly 1021 ---TKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSM 1082
|.|.:.:...||..... ..|..|:| .:
Mouse 664 CTGTSSSASSNPSGGTCPSS-----HSSLTERH------------------------------KI 693
Fly 1083 LHKAGNSQNPMLLKLLNEKSEDDDG---------NGSGGGPGSM---------NNSRQSELMRQL 1129
||:.....:|..:..|:.:.|..|. :|...|..|: ..|:..:|:|.|
Mouse 694 LHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYL 758
Fly 1130 KNPDGGSHGMHRNSASGNMSTEDLKAML--KIQSDPSLNRKRSLNEPDDD--------------- 1177
.:.|... ..::.|:..:|:|..: |.|.||.......:.:|..:
Mouse 759 LDKDEKD-----LRSTPNLCLDDVKVKVEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLD 818
Fly 1178 ------PSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPL------QVKTLPDITSSTV 1230
|:.:::...|| ||..::|...:.....|....|...||. ::..||::....:
Mouse 819 QFDQLLPTLEKAAQLPS-LCETDRMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAI 882
Fly 1231 SSTLAAPGNLISAGSTGPKA-----AANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVY 1290
.:....|| ||...|.| ..|:|: |.|..
Mouse 883 DNQFGQPG----AGDQIPWANNTLTTINQNK-----------------------------PEDQC 914
Fly 1291 LSQQQQQQLQSPQLAFQHQQLATTATTSITTAASTSAAAAAAAAIL-GEGDSELSKL-------- 1346
:|.|..:.|..| |::.......|......:.| |:.::||::|
Mouse 915 ISSQLDELLCPP--------------TTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDK 965
Fly 1347 ------LDSVMEYYP----------DDTPIV----TNAPSEASAINDIQKSLMLDVESAAFGNDL 1391
||.:.|.:| :|.|.: .::||..:.: |..|
Mouse 966 LVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGL------------SGPF---- 1014
Fly 1392 NQQLMMTQQQQHQQQQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQ----Q 1452
|.|:.|:........|........:.....|.:|.|.:|||.|..|.:|.||..|.|| |
Mouse 1015 --QGMVRQKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQ 1077
Fly 1453 NQQHIMQRLEAMRNQG---NQGFQR---PPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQ 1511
|:|.|:.:..|....| ..|.|: |.| |:|| |.| .::|:
Mouse 1078 NRQAILNQFAANAPVGMNMRSGMQQQITPQP--------PLNA------------QML--AQRQR 1120
Fly 1512 QLAAAQQKERLLQQQQKQQLL-----------------------VPENASE-------YWGNSNL 1546
:|.:.|.::|.:.|||:..|: :|:.|.: |..|...
Mouse 1121 ELYSQQHRQRQIIQQQRAMLMRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGT 1185
Fly 1547 QLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQ---LSP 1608
........|.:.|...|.|....|::|...|.|:... ..|.:||...|.:.|.. |.|
Mouse 1186 PPASTSPFSQLAANPEASLATRSSMVNRGMAGNMGGQ-----FGAGISPQMQQNVFQYPGPGLVP 1245
Fly 1609 GRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQ--QQLAYQQQQVGDGGRSNTPF 1671
...|.::|..:.| :...|.| :.|.|...|.|....:..| ...|:||..:|:....:...
Mouse 1246 QGEATFAPSLSPG-SSMVPMP---VPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAV 1306
Fly 1672 GSNSGMQSPGMQNSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQ 1736
.|......||:.|:.....|..| ||| .:|..|||: .|
Mouse 1307 QSQPAPAQPGVYNNMSITVSMAG-----------GNA--NIQNMNPMM---------------GQ 1343
Fly 1737 NQRRGLNSPGAVGPGGNPAAQAALQRQNSFQGQGGGG---ATTPDGSGVGFGGPQSPYGTNVNVF 1798
.|...|..||............||:....:..|.... .|..||:
Mouse 1344 MQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGN------------------ 1390
Fly 1799 QQQQLQRLQRQGSVPQATQHLPGSPRFGSSPGSSNNTDSSAAAGNQQQQQQQQQQQQQ 1856
||:|::|....| |.|.:|.|...:.:.||.... ....:|.|..|.||:...||
Mouse 1391 --QQVQQVQVFADV-QCTVNLVGGDPYLNQPGPLGT--QKPTSGPQTPQAQQKSLLQQ 1443
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