Protein Alignment ZKSCAN2 and CG32772

DIOPT Version :10

• Sequence 1: NP_001012999.3
• Gene: ZKSCAN2 / 342357
• HGNCID: 25677
• Length: 967
• Species: Homo sapiens
• Sequence 2: NP_572196.3
• Gene: CG32772 / 31420
• FlyBaseID: FBgn0052772
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 84/314 - (26%)
• Similarity: 144/314 - (45%)
• Gaps: 56/314 - (17%)

Human   628 AVIEDSCSERMSEEEIVQEPEFQGPPGLLQSPNDFEIGSSIKEDPTQIVYKDMEQHRALIEKSKR 692
            |....|.:.....:.|.|:.:.|.|                          ..:||
  Fly    63 AATSSSTASSSDSDAIAQQQQHQNP--------------------------QQQQH--------- 92

Human   693 VVSQSTDPSKYRKRECISGRQWENLQGIRQGKPMSQPRDLGKAVVHQRPFVGKRPYRLLKYGESF 757
               |::...:.::::..|....|||    |.:..|:..||   :.::.   |..|.    ..::|
  Fly    93 ---QNSQQQQQQQQQMQSSSSSENL----QSQDDSEDVDL---IFNEE---GSCPL----CNKTF 140

Human   758 GRSTRLMCRMTHHK-ENPYKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAH 821
            .|.:.||..:.:|. |..:.|..|.|.|.::.:|..|:||||.::|::|:||||:|...:|...|
  Fly   141 SRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNH 205

Human   822 QRIHTGEKPYRCG--ECGKCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGE 884
            :|:||||:|:.|.  |||:.|:|.::|..|.::|...:.|.|..|.|.||..:..:.|.:.|.|.
  Fly   206 RRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGV 270

Human   885 NPYKCVDC-EKSFNNCTRFREHRRIHTGEKPYGCAQCGKRFSKSSVLTKHREVH 937
            ..|.|..| ||:|...::...|.:.|....||.|.:|.::|.:.:.|.:|.::|
  Fly   271 TGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLKMH 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZKSCAN2	NP_001012999.3	SCAN	41..148	CDD:128708
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..205
		KRAB	<248..289	CDD:214630
		Myb_DNA-bind_4	340..421	CDD:463994
		Myb_DNA-bind_4	497..578	CDD:463994
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	586..626
		COG5048	771..>957	CDD:227381	60/171 (35%)
		C2H2 Zn finger	777..797	CDD:275368	7/19 (37%)
		C2H2 Zn finger	805..825	CDD:275368	9/19 (47%)
		C2H2 Zn finger	833..853	CDD:275368	8/21 (38%)
		C2H2 Zn finger	861..881	CDD:275368	6/19 (32%)
		C2H2 Zn finger	889..909	CDD:275368	6/20 (30%)
		C2H2 Zn finger	917..937	CDD:275368	5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	941..967
CG32772	NP_572196.3	C2H2 Zn finger	133..153	CDD:275368	5/23 (22%)
		C2H2 Zn finger	161..181	CDD:275368	7/19 (37%)
		zf-H2C2_2	173..198	CDD:463886	13/24 (54%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..239	CDD:275368	8/21 (38%)
		SUF4-like	222..>267	CDD:411020	14/44 (32%)
		C2H2 Zn finger	222..240	CDD:411020	6/17 (35%)
		C2H2 Zn finger	247..267	CDD:411020	6/19 (32%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	275..296	CDD:275368	6/20 (30%)
		C2H2 Zn finger	304..324	CDD:275368	5/19 (26%)
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368