Protein Alignment Toll-4 and AT1G63750

DIOPT Version :10

• Sequence 1: NP_523519.2
• Gene: Toll-4 / 34235
• FlyBaseID: FBgn0032095
• Length: 1125
• Species: Drosophila melanogaster
• Sequence 2: NP_001077769.1
• Gene: AT1G63750 / 842679
• AraportID: AT1G63750
• Length: 1131
• Species: Arabidopsis thaliana
• Alignment Length: 1099
• Identity: 202/1099 - (18%)
• Similarity: 360/1099 - (32%)
• Gaps: 385/1099 - (35%)

  Fly     2 EHSKLWD-----LRPEVRERRFKWTSDGQQQQQQQLGWCNNKDDPPNSHQKSKSNNDARNLNSRV 61
            |..|.||     ::...|:..:|..:...:..:..:|.        .:|.|        .:.|.:
plant   157 EDFKKWDNEANMIKKIARDVSYKLNATPSKDFEDMMGL--------EAHLK--------KIQSLL 205

  Fly    62 RV----RARVRVVPGEMRMGDINCSNGLGNIREDYCEI--YLDELGENGTCSIANNEVTTEDYQM 120
            |:    .|.:..:.|...:|....:..|.:...|..::  ::|..|..      ||.:  .||..
plant   206 RLDYKDEALIIGISGPAGIGKSTIARALESRLSDRFQLTCFMDLRGSE------NNGL--HDYGQ 262

  Fly   121 KLVFLKLEINWTSPVFHGWNIFKICNETDYELVIISVLGIRSEVDMRISPAVQYLSLLGIREISG 185
            :   |:|:...         :.|:.|:....:..:.||..|.. |:|:        |:.:.::|
plant   263 Q---LRLQEQL---------LAKVLNQDGTRICHLGVLQQRLS-DLRV--------LIILDDVS- 305

  Fly   186 YDIYLPSVLITEMDVHHANGPKMVTFKYLYDSTVNSVITNNYIRKTMNNTEKIKIYYHNTFEKTT 250
             ||.....|..| ......|.:::......|......|.:.|.....:..|.::|:....||:::
plant   306 -DIKQLKALAKE-TTWFGPGSRIIVTTENKDLLQQRGIDSTYHVGFPSREEALEIFCKFAFEQSS 368

  Fly   251 LTMEKNIFHGKNKMSALIFN-------GLKIKG-----------------LTNNTFENLTSLNTL 291
            ..      |...|::|.|.:       ||.:.|                 |..|..:.:..:..:
plant   369 PP------HAFEKLAARITHLCGNLPLGLCVMGSSLFGKKQDEWEFVVHRLETNPGQEIDDVLRV 427

  Fly   292 IFDNVFLKD-LSFLRSSTL----QSSLTYCIMKVDNMVDLKSFEKF-TNLEIIEVSQYKGFKNFT 350
            .::.:...| :.||..:..    ...|...::..|..:|:.::.|| .|..:||:  |:     |
plant   428 GYERLHENDQMLFLHIAIFFNYRDRDLVEAMLADDGNLDVGNWLKFLINKSLIEI--YR-----T 485

  Fly   351 AFIC----------------EPYKSHCKFTLGINEVACPL-------KCNCSYNRDKSQLEIDCW 392
            ..|.                ||:|.  :..:..||: |.|       .||.
plant   486 GQIVMHKLLQQVGRQAIRRQEPWKR--QILINANEI-CDLLRYEKGTSCNV-------------- 533

  Fly   393 QKNLTTIPSLPVPKKGSSALVFQSNLLAELP--DNSLEGYHNLKSLDVSYNQLTSLSVSQLPESL 455
                             |.:.|.::.::|:.  |.:.:..|:|:.|.|..::
plant   534 -----------------SGISFDTSGISEVTICDGAFKRLHDLRFLHVYKSR------------- 568

  Fly   456 HYLDIRHNKITTLSPQVVEYLYSVNVFNQYGNKWSIYCDEYHLQEFFWYKAKLLRIKTSKFQTIM 520
               |..:|::..  |:.||:...:.:.:     |:.            |.:|.|. .|...:.:
plant   569 ---DDGNNRVHI--PEKVEFPPRLRLLH-----WAA------------YPSKSLP-PTFNLECL- 609

  Fly   521 EYIELSSKGSFVENFF--VQNIDQL-YLEANED----EIIDAFGPSD-KYFNLKLMEALNHAIWL 577
              :||:.:.|.||..:  .|::..| |::..|.    |:.|....:: :||.|...|:|......
plant   610 --VELNMRESLVEKLWEGTQHLKNLKYMDLTESKNLKELPDLSNATNLEYFYLDNCESLVEIPSS 672

  Fly   578 FSGEFDEIILHHLNSPCPYRCSCCFEWHTGEFLINCRNLSLDIYPRLPNSIPYKTTLYLDRNEIR 642
            |:         ||:.         .||..   :.||  ::|.:.|...|....|.......:.:|
plant   673 FA---------HLHK---------LEWLE---MNNC--INLQVIPAHMNLTSVKQVNMKGCSRLR 714

  Fly   643 KLTNTESLVVAGHASIHKLHMSQNL-LRELPLHLLPE-NITYLDVRNNLLKYLDDGVIAFLEYRE 705
            |..     |::.|  |..|.:|.|. |.::|..:... ::.|||:.:|             |..:
plant   715 KFP-----VISRH--IEALDISDNTELEDMPASIASWCHLVYLDMSHN-------------EKLQ 759

  Fly   706 NITKIELSGNPWECNCKAKAFLSFLRRHEPMEYETVLRRVEITDDKCPEDCI--------CCVDT 762
            .:|::..|                 .||..:.|         ||.:...|||        .|:
plant   760 GLTQLPTS-----------------LRHLNLSY---------TDIESIPDCIKALHQLEELCL-- 796

  Fly   763 SNSDSLAYVVD--CSGKEL-----SEIPQLPTPTY---------------GQTTLVFERNSLKKW 805
            |....||.:.|  ||.|.|     ..:..:.:|.|               |:......|.|....
plant   797 SGCTRLASLPDLPCSIKALEAEDCESLESVSSPLYTPSARLSFTNCFKLGGEAREAIIRRSSDST 861

  Fly   806 PSSLLPGYSSVTRFYLAHNRLSDIDQLPDKLEYLDISNNNFSALDDRVRGFLQKRMNSSQLQLSL 870
            .|.||||......|                              |.|.:|      ||..:.|.|
plant   862 GSVLLPGREVPAEF------------------------------DHRAQG------NSLSILLPL 890

  Fly   871 FGNPWTCRCEDKDFLVFV----KEQAKNIANASAIQCIDTGRSLIEVEETDICPSVLIYYTSLAV 931
            .||        ..|:|.|    :.....::|.|.:.|...|.|....||.||
plant   891 GGN--------SQFMVCVVISPRHDITKMSNESELLCRINGESCSYDEEFDI------------- 934

  Fly   932 SLLIIALSINVFICFRQPIMIWFYEHEICLSLAARRELDEDKKYDAFLSFTHKDEDLIE 990
                    ::|..|.|:.:.|:   |...|.: .|.|...:..:: |.|...:|.|:||
plant   935 --------VDVSNCRREHLFIF---HSGLLRM-GRSEAGTEMVFE-FSSALQEDFDIIE 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-4	NP_523519.2	LRR	210..>470	CDD:443914	49/314 (16%)
		leucine-rich repeat	264..287	CDD:275380	7/46 (15%)
		leucine-rich repeat	288..308	CDD:275380	3/20 (15%)
		leucine-rich repeat	309..334	CDD:275380	5/29 (17%)
		leucine-rich repeat	335..386	CDD:275380	14/73 (19%)
		PRK15370	<381..>482	CDD:185268	13/102 (13%)
		leucine-rich repeat	388..408	CDD:275380	0/19 (0%)
		leucine-rich repeat	412..432	CDD:275378	3/21 (14%)
		LRR	<416..591	CDD:443914	34/184 (18%)
		leucine-rich repeat	433..454	CDD:275378	3/20 (15%)
		leucine-rich repeat	455..478	CDD:275378	5/22 (23%)
		leucine-rich repeat	479..490	CDD:275378	0/10 (0%)
		leucine-rich repeat	632..657	CDD:275378	4/24 (17%)
		leucine-rich repeat	658..679	CDD:275378	6/22 (27%)
		leucine-rich repeat	680..706	CDD:275378	5/25 (20%)
		PCC	684..>771	CDD:188093	17/94 (18%)
		leucine-rich repeat	707..719	CDD:275378	2/11 (18%)
		leucine-rich repeat	771..791	CDD:275380	7/41 (17%)
		PRK15370	<793..>877	CDD:185268	17/83 (20%)
		leucine-rich repeat	793..815	CDD:275378	7/21 (33%)
		leucine-rich repeat	816..835	CDD:275378	1/18 (6%)
		leucine-rich repeat	836..859	CDD:275378	3/22 (14%)
		TIR	974..1110	CDD:214587	6/17 (35%)
AT1G63750	NP_001077769.1	PLN03210	6..948	CDD:215633	191/1060 (18%)
		leucine-rich repeat	559..608	CDD:275380	13/84 (15%)
		leucine-rich repeat	609..631	CDD:275380	6/24 (25%)
		leucine-rich repeat	632..654	CDD:275380	5/21 (24%)
		leucine-rich repeat	655..678	CDD:275380	8/31 (26%)
		leucine-rich repeat	679..712	CDD:275380	8/37 (22%)
		leucine-rich repeat	713..746	CDD:275380	10/39 (26%)
		leucine-rich repeat	768..790	CDD:275380	8/30 (27%)