DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-zeta and Kirrel3

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:XP_006510620.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:461 Identity:94/461 - (20%)
Similarity:152/461 - (32%) Gaps:153/461 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 FTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWM-------------HFEQSAILTVHNHVITRNP 166
            |::..::..|.:|:.|.|.|::.....: |.|:             .:.|  .|.|.||      
Mouse    50 FSQQPQDQVVVSGQPVTLLCAIPEYDGF-VLWIKDGLALGVGRDLSSYPQ--YLVVGNH------ 105

  Fly   167 RISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIV 231
             :|..|         :|.|.....:|...|.||......:::...|.|:|||:....|....:.:
Mouse   106 -LSGEH---------HLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPIILGGPVISL 160

  Fly   232 REGANISLRCRA-SGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITR---------ISRLD 286
            |.|..::|.|.| :..|...|.|.|         |..::|   |.|...|.         :|.|.
Mouse   161 RAGDPLNLTCHADNAKPAASIIWLR---------KGEVIN---GATYSKTLLRDGKRESIVSTLF 213

  Fly   287 MG--------AYLCIASN-GVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPT 342
            :.        :.:|.|:| .:|......:.:.:..||::.:..:.....|...||..|..:|:|.
Mouse   214 ISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNIVTFHCSAKANPA 278

  Fly   343 SLNY-WTRGEGPIIHDS----------HKYKVE-------------------------------- 364
            ...| |.: .|.||.::          :.|..|                                
Mouse   279 VTQYRWAK-RGHIIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQ 342

  Fly   365 --------------ATVGLPA-------------YKTHMKLTIINVSSGDDGIYKCVAKNPR--- 399
                          |.:|.|:             ......||:.:|...|.|.|.|.|..||   
Mouse   343 SLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGA 407

  Fly   400 GETDGIIRLYVSYPPTTASSGIYSTDTH---WGENGINNNYAYGGPDSTRSIYAQDKNTRYQSNL 461
            ||.:  :.|.|:.||.     |.||.|.   .||.|....:....|...|..::      ::.|:
Mouse   408 GERE--VTLTVNGPPI-----ISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWS------WKENV 459

  Fly   462 NEIGLS 467
            .|.|.|
Mouse   460 LESGTS 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 22/108 (20%)
Ig 130..200 CDD:143165 17/82 (21%)
I-set 226..310 CDD:254352 20/102 (20%)
IGc2 233..298 CDD:197706 18/83 (22%)
Ig 313..410 CDD:299845 31/169 (18%)
IG_like 325..410 CDD:214653 29/157 (18%)
Kirrel3XP_006510620.1 IG_like 54..143 CDD:214653 21/107 (20%)
Ig strand A' 56..60 CDD:409353 0/3 (0%)
Ig strand B 64..71 CDD:409353 3/6 (50%)
Ig strand C 78..82 CDD:409353 2/3 (67%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
Ig strand D 97..101 CDD:409353 1/5 (20%)
Ig strand E 104..116 CDD:409353 6/27 (22%)
Ig strand G 132..143 CDD:409353 1/10 (10%)
IgI_2_KIRREL3-like 149..246 CDD:409416 21/108 (19%)
Ig strand B 166..170 CDD:409416 1/3 (33%)
Ig strand C 180..184 CDD:409416 1/3 (33%)
Ig strand E 210..214 CDD:409416 2/3 (67%)
Ig strand F 224..229 CDD:409416 1/4 (25%)
Ig strand G 239..242 CDD:409416 0/2 (0%)
Ig <267..334 CDD:416386 12/67 (18%)
Ig strand B 267..274 CDD:409353 3/6 (50%)
Ig strand C 279..286 CDD:409353 2/6 (33%)
Ig strand C' 288..291 CDD:409353 1/2 (50%)
Ig strand D 298..302 CDD:409353 0/3 (0%)
Ig strand E 304..310 CDD:409353 1/5 (20%)
Ig strand G 321..334 CDD:409353 0/12 (0%)
Ig 335..416 CDD:416386 16/82 (20%)
Ig strand A' 343..347 CDD:409353 0/3 (0%)
Ig strand B 350..360 CDD:409353 1/9 (11%)
Ig strand C 365..371 CDD:409353 0/5 (0%)
Ig strand E 381..387 CDD:409353 2/5 (40%)
IgI_5_KIRREL3 418..515 CDD:409479 15/59 (25%)
Ig strand B 436..440 CDD:409479 1/3 (33%)
Ig strand C 450..454 CDD:409479 1/3 (33%)
Ig strand E 481..485 CDD:409479
Ig strand F 496..501 CDD:409479
Ig strand G 509..512 CDD:409479
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.