DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Negr1

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:XP_038958934.1 Gene:Negr1 / 59318 RGDID:708416 Length:362 Species:Rattus norvegicus


Alignment Length:302 Identity:92/302 - (30%)
Similarity:141/302 - (46%) Gaps:26/302 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 IENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISV-THDKHDRHRTWY 182
            ::|:.|..|....|.|.::: |:.|.||::  :|:|:.......:.:||:|: |.:|.|    :.
  Rat    39 VDNMLVRKGDTAVLRCYLED-GASKGAWLN--RSSIIFAGGDKWSVDPRVSISTLNKRD----YS 96

  Fly   183 LHINNVHEEDRGRYMCQINTV-TAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGS 246
            |.|.||...|.|.|.|.:.|. |.:|...:|.|.|||.|.|  .|:|:.:.||.|::|.|.|:|.
  Rat    97 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYD--ISNDMTINEGTNVTLTCLATGK 159

  Fly   247 PRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVD 311
            |.|.|.|:     .|:.:.....|   |..|:|..|:|...|.|.|.|.|.|.....|:::|.|:
  Rat   160 PEPAISWR-----HISPSAKPFEN---GQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVVVN 216

  Fly   312 FPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKVEATVGLPAYKTHM 376
            |.|.:.........| |.:..|.|.....|.....|.:||      ...:..:..:.:..:.|..
  Rat   217 FAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGE------KRLFNGQQGIIIQNFSTRS 274

  Fly   377 KLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTAS 418
            .||:.||:....|.|.|||.|..|.|:..:.|.....|||:|
  Rat   275 ILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNQIIEPTTSS 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 30/97 (31%)
Ig 130..200 CDD:143165 22/70 (31%)
I-set 226..310 CDD:254352 28/83 (34%)
IGc2 233..298 CDD:197706 23/64 (36%)
Ig 313..410 CDD:299845 23/96 (24%)
IG_like 325..410 CDD:214653 22/84 (26%)
Negr1XP_038958934.1 FR1 38..55 CDD:409353 4/15 (27%)
Ig strand A' 40..46 CDD:409353 2/5 (40%)
IG_like 41..129 CDD:214653 29/94 (31%)
Ig strand B 48..56 CDD:409353 2/7 (29%)
CDR1 56..60 CDD:409353 0/4 (0%)
FR2 61..68 CDD:409353 3/8 (38%)
Ig strand C 61..67 CDD:409353 3/5 (60%)
CDR2 69..79 CDD:409353 2/9 (22%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 14/38 (37%)
Ig strand D 84..91 CDD:409353 3/6 (50%)
Ig strand E 94..100 CDD:409353 2/9 (22%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/8 (25%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A' 139..144 CDD:409353 2/4 (50%)
IGc2 146..204 CDD:197706 23/65 (35%)
Ig strand B 150..157 CDD:409353 2/6 (33%)
Ig strand C 163..168 CDD:409353 2/9 (22%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig strand G 207..215 CDD:409353 2/7 (29%)
Ig_3 219..295 CDD:404760 19/82 (23%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 1/3 (33%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337182
Domainoid 1 1.000 45 1.000 Domainoid score I11853
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
109.900

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