DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and igsf9bb

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	400	Identity:	105/400 - (26%)
Similarity:	154/400 - (38%)	Gaps:	109/400 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 SGTGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSV---KNLGS 141
            |..|:...|::|                 |.|||:|      ||..||..|.|||.|   .|...
Zfish    14 STRGTAAQGAHG-----------------VREEPQF------VTSRAGETVILGCDVVHPLNGQP 55

  Fly   142 YKVAWMHFEQSAILTVH-----NHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQIN 201
            |.|.|..|.......::     .||   :|..:.....|.:..   |.|..|..||:|.|.|::
Zfish    56 YVVEWFKFGVPIPFFINFRFYPPHV---DPEYAGRASLHGKSS---LRIERVRSEDQGWYECKV- 113

  Fly   202 TVTAKTQFG--------YLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSPRPIIKWKRDDN 258
             :..:.|:.        :|.|..||...|: ....|..:||.:|:|.|.|.|:|:|.:.|.|:.|
Zfish   114 -LMLEQQYHTFHNGSWVHLTVNAPPTFTDT-PPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGN 176

  Fly   259 SRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLV 323
            . :..:..:.|::   .:|.:..|||.|.|||.|.|.:.....| ...::.|..||.::.|
Zfish   177 P-VQDSTKYKVSD---GSLTLVSISREDRGAYTCRAYSEQGEAV-HTTRLLVQGPPFIVSP---- 232

  Fly   324 GAPEGFNVTIE------CFTEAHPTSLNY---WTRG----------------EGPII------HD 357
              ||...|.|.      |..||:|.:|.|   |...                :|.:|      .|
Zfish   233 --PENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPED 295

  Fly   358 SHKYKVEA--TVGLP----AYKT-HMKLTIIN------VSSGDDGIYKC-VAKNP-----RGETD 403
            :.||....  ::|.|    ||.| |....:||      |:.|..|..:| |..||     :.:.|
Zfish   296 AGKYTCSPSNSLGRPPSASAYLTVHYPARVINMPPVIYVAIGLPGYIRCPVDANPPVTSVKWKKD 360

  Fly   404 GIIRLYVSYP 413
            |:......||
Zfish   361 GLPLRIEKYP 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	29/111 (26%)
		Ig	130..200	CDD:143165	22/77 (29%)
		I-set	226..310	CDD:254352	25/83 (30%)
		IGc2	233..298	CDD:197706	23/64 (36%)
		Ig	313..410	CDD:299845	36/146 (25%)
		IG_like	325..410	CDD:214653	33/134 (25%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	28/94 (30%)
		Ig	41..113	CDD:143165	22/77 (29%)
		IG_like	144..223	CDD:214653	25/83 (30%)
		IGc2	151..208	CDD:197706	22/60 (37%)
		I-set	227..319	CDD:254352	22/97 (23%)
		Ig	<263..319	CDD:299845	10/55 (18%)
		Ig_2	326..414	CDD:290606	12/44 (27%)
		IG_like	329..403	CDD:214653	10/41 (24%)
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010