DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and lrit1a

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001018174.2 Gene:lrit1a / 553943 ZFINID:ZDB-GENE-040924-5 Length:643 Species:Danio rerio


Alignment Length:345 Identity:69/345 - (20%)
Similarity:117/345 - (33%) Gaps:91/345 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 GANISLRCRASGSPRPIIKWKRDD----NSRIAI--NKNHIVNEWEGDTLEITRISRLDMGAYLC 292
            |.|:.|||...|.|.|.:.|:|.|    |..:.:  :|..||  |  ..|.:..:|..|.|.|:|
Zfish   266 GNNVLLRCGTVGVPIPELAWRRADGKPLNGTVLLENSKEGIV--W--SILSVPAVSYRDTGKYIC 326

  Fly   293 IASN--GVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPII 355
            .|:|  |....|...|               :..||:..|.|::...:......|       .::
Zfish   327 KATNYAGSAEAVISLI---------------I
NDAPKMENPTLDPKPKLKSKKPN-------TMV 369

  Fly   356 HDSHKYKVEATVGLPAYKTHMKLT-IINVSSGDDGIYKCVAKNPRGET-----DGIIRLYVSYPP 414
            ..:::.|..||...|..|..:.|: .::.:....|:....|.|.|..|     ||.:...:|...
Zfish   370 KAAYQEKHIATYVSPTPKNGLPLSGTVSYTGPYPGMESDNAANSRMNTQTASPDGFLETNLSNLA 434

  Fly   415 TTASS-----------------GIYSTDTHWGENGINNN------YAYGGPDSTRSIYAQDKNTR 456
            ...||                 ..|:...:|......|.      ||..|....|.|.....|.|
Zfish   435 ANTSSLQQDPDRVVRSVKVIGDTDYTVCLNWRAPTAKNTTAFSVLYAVFGERDMRRINVSPGNNR 499

  Fly   457 YQSNLNEIGLSEQ---------KSFLDKTQNPLLANGNANEADAESNGARGHNPSMAIAWLFVVI 512
            ....    ||..:         |..:.|.:..::.   :.:|.|.:||.:            .:|
Zfish   500 IVIE----GLVPKTKYIACVCVKGLIPKKEQCVIF---STDAAASANGTQ------------KLI 545

  Fly   513 ATLLLTIRSAVGSSHSLSLC 532
            ..:::|:...:....::.:|
Zfish   546 NVVVITVACVIAVPLTVIVC 565

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653
Ig 130..200 CDD:143165
I-set 226..310 CDD:254352 27/83 (33%)
IGc2 233..298 CDD:197706 24/71 (34%)
Ig 313..410 CDD:299845 18/102 (18%)
IG_like 325..410 CDD:214653 18/90 (20%)
lrit1aNP_001018174.2 leucine-rich repeat 61..84 CDD:275378
LRR_8 63..119 CDD:290566
LRR_RI <77..175 CDD:238064
leucine-rich repeat 85..108 CDD:275378
LRR_8 108..167 CDD:290566
leucine-rich repeat 109..132 CDD:275378
leucine-rich repeat 133..156 CDD:275378
leucine-rich repeat 157..170 CDD:275378
LRRCT 199..243 CDD:214507
I-set 252..343 CDD:254352 27/95 (28%)
Ig 259..333 CDD:299845 24/70 (34%)
fn3 448..515 CDD:278470 12/70 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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