DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-zeta and iglon5

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	302	Identity:	89/302 - (29%)
Similarity:	141/302 - (46%)	Gaps:	36/302 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 EFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDRH 178
            ||....:|:||..|.:|.|.|.:....::| ||::  :|.||.......:.:.|:|:   :::.:
Zfish    28 EFGHLPDNITVLEGESVVLRCKIDEEVTHK-AWLN--RSNILFTGTDKWSLDSRVSL---ENNNN 86

  Fly   179 RTWYLHINNVHEEDRGRYMCQINTVT-AKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCR 242
            ..:.:.|..|...|.|.|.|...... .:|...||.|.||..|.:  .|.|..|.||.:::|.|.
Zfish    87 SDFSIRIERVMVADEGPYTCSFQARNKPRTAHVYLIVQVPARIVN--ISQDKSVNEGEDVNLFCL 149

  Fly   243 ASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIK 307
            |.|.|.|.|.||.        .|..::|  ||:.||||.|.|.....:.||.:|||.|..::::|
Zfish   150 AVGRPEPTITWKD--------FKYGLLN--EGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVK 204

  Fly   308 VSVDFPPMLL----IPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGE-GPIIHDSHKYKVEATV 367
            |:|::||::.    :|.|:     |....:.|...|.||:...|.|.: .|:..|:       |:
Zfish   205 VTVNYPPIITDVKNMPAQV-----GKTAILRCEAMAVPTASFEWYRDDRRPVESDN-------TL 257

  Fly   368 GLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLY 409
            .:...||...|...||:....|.|.|.|.|..|.::..:.|:
Zfish   258 KIKNEKTRSLLLFTNVTEKHFGNYTCFASNRLGASNASMLLF 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	25/96 (26%)
		Ig	130..200	CDD:143165	17/69 (25%)
		I-set	226..310	CDD:254352	32/83 (39%)
		IGc2	233..298	CDD:197706	24/64 (38%)
		Ig	313..410	CDD:299845	26/102 (25%)
		IG_like	325..410	CDD:214653	22/86 (26%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	24/95 (25%)
		Ig	35..123	CDD:299845	24/93 (26%)
		Ig	125..>183	CDD:299845	27/69 (39%)
		I-set	128..207	CDD:254352	33/90 (37%)
		IG_like	217..298	CDD:214653	23/92 (25%)
		ig	223..296	CDD:278476	21/84 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576314
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850