DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and opcml

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	293	Identity:	100/293 - (34%)
Similarity:	148/293 - (50%)	Gaps:	27/293 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 ENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDRHRTWYLH 184
            :|:||..|.:..|.||:.|..| :|||::  ::.||...|...:.:||:.:.:...:.:.   :.
Zfish    40 DNITVRQGDSAVLKCSMDNKVS-RVAWLN--RTTILFTGNEKWSLDPRVVLLNTAVNEYS---IK 98

  Fly   185 INNVHEEDRGRYMCQI--NTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRCRASGSP 247
            |.||:..|.|.|:|.|  |.....|:. :|.|.||..|.:  .|:||.|.||:|:||.|.|.|.|
Zfish    99 ILNVNLYDEGPYVCSILTNKKPESTKV-HLIVQVPARIVN--VSTDVSVNEGSNVSLMCLAIGRP 160

  Fly   248 RPIIKWK-RDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVD 311
            .|.|.|| |....      |.||.  ||:.:|:|.|::...|:|.||.||.:.|...:.::|:|:
Zfish   161 EPSILWKFRSSKG------NRIVT--EGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVN 217

  Fly   312 FPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKVEATVGLPAYKTHM 376
            :||::..... .|...|....:.|...|.|.:...|.:||..|::..:..|:| ..|    |..|
Zfish   218 YPPVISRARS-TGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNGVKIE-NKG----KQSM 276

  Fly   377 KLTIINVSSGDDGIYKCVAKNPRGETDGIIRLY 409
             ||..|||..|.|.|.|||.|..|.|:..|.||
Zfish   277 -LTFFNVSEEDYGNYTCVAINTLGITNASIILY 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	29/97 (30%)
		Ig	130..200	CDD:143165	20/69 (29%)
		I-set	226..310	CDD:254352	34/84 (40%)
		IGc2	233..298	CDD:197706	28/65 (43%)
		Ig	313..410	CDD:299845	33/97 (34%)
		IG_like	325..410	CDD:214653	30/85 (35%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	28/94 (30%)
		IG_like	41..129	CDD:214653	28/94 (30%)
		IG_like	139..216	CDD:214653	34/84 (40%)
		IGc2	146..202	CDD:197706	26/63 (41%)
		I-set	219..307	CDD:254352	31/94 (33%)
		ig	223..307	CDD:278476	29/90 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.800