DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and DIP-gamma

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	146/371 - (39%)
Similarity:	202/371 - (54%)	Gaps:	44/371 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHD 176
            :|||..:|.|||.||||...|.|||:|||..||.|:......:|.:...|:|.|.||||.|  .|
  Fly    38 DPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMH--QD 100

  Fly   177 RHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREGANISLRC 241
            .| ||.|.|:.:.|.|||.|||||||...|.|.|.::|.|||:|.:..||:|:.|:||.:.:|.|
  Fly   101 MH-TWKLKISKLRESDRGCYMCQINTSPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTC 164

  Fly   242 RASGSPRPIIKWKRDDNSRIAINKNHI-----VNEWEGDTLEITRISRLDMGAYLCIASNGVPPT 301
            :|:|:|:|.:.|:|:|...|.|.|...     |..:.|.:|.:.|:.|..||||||||||.|||.
  Fly   165 KATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPA 229

  Fly   302 VSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRG---------------- 350
            ||||:.:||.|.||:..|.||:|.|.|.:|.:||..||.|:.::||.:|
  Fly   230 VSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLE 294

  Fly   351 ---EGP-IIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLY-- 409
               .|| ::.|..||.:  |.....|:..|.|.:.:.|..|.|.|.||:.|..|..:|.:|||
  Fly   295 SGSPGPEMLLDGPKYGI--TERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEI 357

  Fly   410 VSYPPTTASSGIYSTDTHWGENGINNNYAYGGPDSTRSIYAQDKNT 455
            ..:|..:||:     |.|.       ||..|..::.|:....::.|
  Fly   358 KLHPGASASN-----DDHL-------NYIGGLEEAARNAGRSNRTT 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	47/95 (49%)
		Ig	130..200	CDD:143165	32/69 (46%)
		I-set	226..310	CDD:254352	39/88 (44%)
		IGc2	233..298	CDD:197706	29/69 (42%)
		Ig	313..410	CDD:299845	38/118 (32%)
		IG_like	325..410	CDD:214653	32/106 (30%)
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	47/94 (50%)
		Ig	47..129	CDD:299845	43/84 (51%)
		Ig	140..238	CDD:299845	43/97 (44%)
		IG_like	247..355	CDD:214653	34/109 (31%)
		Ig	256..351	CDD:299845	27/96 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12510
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102261at50557
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8732
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	9	8.970