DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and LRIT1

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:300 Identity:63/300 - (21%)
Similarity:92/300 - (30%) Gaps:123/300 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 GANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGV 298
            |....|||.|:|.|.|.:.|:|                                       :||.
Human   268 GGTALLRCGATGVPGPEMSWRR---------------------------------------ANGR 293

  Fly   299 PPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKV 363
            |                             .|.|:.....:..||   ||               
Human   294 P-----------------------------LNGTVHQEVSSDGTS---WT--------------- 311

  Fly   364 EATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPT-TASSGIYSTDTH 427
              .:||||           ||..|.|.|.|.|||..|.::.:|.|.|:.||| |..||  |....
Human   312 --LLGLPA-----------VSHLDSGDYICQAKNFLGASETVISLIVTEPPTSTEHSG--SPGAL 361

  Fly   428 WGENGINNNYAYGGPDSTRSIYAQDKNTRYQSNLNEIGLSEQKSFLDKTQNPLLANGNANEADAE 492
            |...|       ||.::  :.|......|:...:.:..:......:..|:..|.......:|..|
Human   362 WARTG-------GGGEA--AAYNNKLVARHVPQIPKPAVLATGPSVPSTKEELTLEHFQMDALGE 417

  Fly   493 -SNGARGHNPSMAIAWLFVVIATLLLTIRSAVGSSHSLSL 531
             |:|..|  ||.         |.::.:::....:.||:||
Human   418 LSDGRAG--PSE---------ARMVRSVKVVGDTYHSVSL 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653
Ig 130..200 CDD:143165
I-set 226..310 CDD:254352 13/75 (17%)
IGc2 233..298 CDD:197706 11/63 (17%)
Ig 313..410 CDD:299845 22/96 (23%)
IG_like 325..410 CDD:214653 22/84 (26%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 35/175 (20%)
IG_like 267..345 CDD:214653 35/175 (20%)
FN3 431..498 CDD:214495 3/15 (20%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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