DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-zeta and Lrit1

DIOPT Version :9

Sequence 1:NP_723441.2 Gene:DIP-zeta / 34231 FlyBaseID:FBgn0051708 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:370 Identity:79/370 - (21%)
Similarity:121/370 - (32%) Gaps:103/370 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 PEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHV-----ITRNPRISVTH 172
            ||...::||:|.....|.:|....:.|..   .|.|.:....|:.| |.     :..||.:.   
Mouse   148 PEAAHFLENLTFLDLSNNQLMRLPEELLD---VWAHLKTGPFLSGH-HARLILGLQDNPWVC--- 205

  Fly   173 DKHDRHRTWYLHI-------NNVHEEDRGRYMCQINTVTAKTQFGYLNV--VVPPNIDDSLSSSD 228
               |......:|:       |.:..|.|.|  |......|...|..|.:  ...|.:...::|  
Mouse   206 ---DCRLYDLVHLLDGWVSSNLIFIEARLR--CASPRSLAGVAFSQLELRKCQSPELRPGVTS-- 263

  Fly   229 VIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDT---LEITRISRLDMGAY 290
            :|...|:.:.|||.|:|.|.|.:.|:| .|.|......|.....:|.:   |::..:|..|.|.|
Mouse   264 IISPLGSTVLLRCGATGIPGPEMSWRR-ANGRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDY 327

  Fly   291 LCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNY-------WT 348
            :|.|.|                         .:||.|   ..|........||..|       |.
Mouse   328 ICQAKN-------------------------FLGASE---TLISLIVTEPQTSTGYSGIPGVLWA 364

  Fly   349 R-GEGP-------------IIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPR 399
            | |||.             :.|......:.....:|:.|.  :|.:.|......|.:   ::.|.
Mouse   365 RTGEGAEAAAYNNKLVARHVPHMPEHVALATKPSMPSIKE--ELALQNFQMDVPGEF---SREPS 424

  Fly   400 --------------GETDGIIRLYVSYPP---TTASSGIYSTDTH 427
                          |:|...:.|....|.   |||.|.:|:...|
Mouse   425 EHQEAQMVRSLKVVGDTYHSVSLVWKAPQAGNTTAFSVLYAVFGH 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-zetaNP_723441.2 IG_like 120..216 CDD:214653 23/109 (21%)
Ig 130..200 CDD:143165 16/81 (20%)
I-set 226..310 CDD:254352 24/86 (28%)
IGc2 233..298 CDD:197706 22/67 (33%)
Ig 313..410 CDD:299845 22/131 (17%)
IG_like 325..410 CDD:214653 21/119 (18%)
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..>176 CDD:290566 8/27 (30%)
LRR_4 131..172 CDD:289563 7/23 (30%)
LRR 4 132..153 2/4 (50%)
leucine-rich repeat 133..156 CDD:275378 2/7 (29%)
LRR 5 156..177 5/23 (22%)
leucine-rich repeat 157..180 CDD:275378 5/25 (20%)
leucine-rich repeat 181..205 CDD:275378 5/24 (21%)
TPKR_C2 201..>241 CDD:301599 9/47 (19%)
Ig 258..346 CDD:299845 28/118 (24%)
IG_like 268..346 CDD:214653 26/106 (25%)
FN3 432..502 CDD:214495 10/38 (26%)
LRR 6 526..549
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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