DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and zig-8

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	55/209 - (26%)
Similarity:	83/209 - (39%)	Gaps:	49/209 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISV 170
            :|:|.|.|.:                |.|||.....:::||......|:||..|...||:||..|
Worm    45 VNVVAENPAY----------------LHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQV 93

  Fly   171 THDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVREG- 234
            :....:   .|.|::....::|.|.|:|:||.........||.|:.||     |.|...:.::.
Worm    94 SKKSAN---IWVLNLRRAEQQDSGCYLCEINDKHNTVYAVYLKVLEPP-----LPSPSSLQKKST 150

  Fly   235 ---ANIS-----LRCRASGSPRP----IIKWKRDDNSRIAINKNHI------VNEWEGDTLEITR 281
               ||:|     |.|..:.:.:.    .:.|.||.|:   ||.|..      |....|..:|..|
Worm   151 KLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNT---INFNDTEKYILKVKRDAGVVIETMR 212

  Fly   282 ISRLDM---GAYLC 292
            |.:..|   |.|.|
Worm   213 IRKATMEDDGNYAC 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	26/95 (27%)
		Ig	130..200	CDD:143165	21/69 (30%)
		I-set	226..310	CDD:254352	22/89 (25%)
		IGc2	233..298	CDD:197706	21/82 (26%)
		Ig	313..410	CDD:299845
		IG_like	325..410	CDD:214653
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	25/81 (31%)
		Ig	55..129	CDD:143165	23/76 (30%)
		ig	158..229	CDD:278476	18/72 (25%)
		IG_like	158..227	CDD:214653	18/72 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810