DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and zig-7

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_491451.2	Gene:	zig-7 / 172096	WormBaseID:	WBGene00006984	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	59/236 - (25%)
Similarity:	98/236 - (41%)	Gaps:	49/236 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 SNLNIVVEEPEFTEYIENVTVPAGRNVK-LGCSVKNLGSY-KVAWMHFEQSAILTVHNHVITRNP 166
            ||| .||..||......|.|:.|  |:: |.|..:|||.: .|.:..|.:.:...|....:.:.
Worm    27 SNL-AVVGSPESHVGTPNKTLYA--NIQNLWCGAQNLGEHIDVEYGEFTRLSDGKVFKGTVNQG- 87

  Fly   167 RISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNID--DSLSSSDV 229
                         ..||.|.....:..|||.|::.|:..:...|.|.:.:||.:|  .::..|:|
Worm    88 -------------KVYLEIGKASVKVAGRYRCEVRTLDKEIHSGNLIIYMPPVLDFPAAVRVSEV 139

  Fly   230 IVR-------------EGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITR 281
            :..             .|..:.|.|....:|.|:::|::  |.....|.:.|  |::|:.|.:..
Worm   140 LNARPPHVIGAERRGLHGERMVLECPVLANPEPMVRWEK--NGEPLGNSDSI--EYDGNNLILNS 200

  Fly   282 ISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQL 322
            ::...:|.|.||..|..|        :.||.|   .||||:
Worm   201 LTEDHIGKYRCIGDNSFP--------LFVDGP---AIPHQI 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	22/97 (23%)
		Ig	130..200	CDD:143165	15/71 (21%)
		I-set	226..310	CDD:254352	20/96 (21%)
		IGc2	233..298	CDD:197706	17/64 (27%)
		Ig	313..410	CDD:299845	5/10 (50%)
		IG_like	325..410	CDD:214653
zig-7	NP_491451.2	IGc2	157..216	CDD:197706	16/62 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910