DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and Kirrel

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	430	Identity:	98/430 - (22%)
Similarity:	157/430 - (36%)	Gaps:	87/430 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EPEFTEYIENVTVPAGRNVKLGCSVKN---------------LGSYKVAWMHFEQSAILTVHNHV 161
            :..|::...:.||.||:...|.|.:.|               :|....||
Mouse    52 QTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAW--------------- 101

  Fly   162 ITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNIDDSLSS 226
                ||..|........  :.|.|.:....|...|.||......:::...|.|::||........
Mouse   102 ----PRYRVVGSADAGQ--YNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGG 160

  Fly   227 SDVIVREGANISLRCRA-SGSPRPIIKWKRDDNSRI-AINKNHIVNEWEGDTLEITRI----SRL 285
            ..::::.|...:|.||| :..|...|.|.||...:. |:....::.:.:.:| .|:::    :.|
Mouse   161 PVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRET-TISQLLIEPTDL 224

  Fly   286 DMG-AYLCIASN-GVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNY-W 347
            |:| .:.|.:.| .:|......|::.|..||.:.:..:.....||..|...|...|:|..|.| |
Mouse   225 DIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRW 289

  Fly   348 TRGEGPIIHDSHKYKVEATVGLPAYKTHMKLTIIN-VSSGDDGIYKCVAKNPRGETDGIIRLYVS 411
            .:| |.:|.|:|:.:.|..|....:...:...:.| |.|.:......|...||         .|.
Mouse   290 AKG-GFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPR---------IVV 344

  Fly   412 YP-PTTASSGIYSTDT-HWGENGINNNYAYGGPDSTRSIYAQDKN--TRYQSNLNEIGLSEQKSF 472
            || |||...|...|.| .|          .|.|..|.:...:|.|  .|...:..|..||.|
Mouse   345 YPKPTTTDIGSDVTLTCVW----------VGNPPLTLTWTKKDSNMGPRLPGSPPEANLSAQ--- 396

  Fly   473 LDKTQNPLLANGN------ANEADAESNGARGHNPSMAIA 506
                   :|:|.|      ..:|||.:...|...|.:.:|
Mouse   397 -------VLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVA 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	21/110 (19%)
		Ig	130..200	CDD:143165	14/84 (17%)
		I-set	226..310	CDD:254352	20/91 (22%)
		IGc2	233..298	CDD:197706	18/72 (25%)
		Ig	313..410	CDD:299845	24/98 (24%)
		IG_like	325..410	CDD:214653	22/86 (26%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	21/114 (18%)
		Ig2_KIRREL3-like	170..251	CDD:143236	19/81 (23%)
		Ig	255..336	CDD:386229	20/81 (25%)
		Ig_3	340..421	CDD:372822	28/109 (26%)
		Ig5_KIRREL3	439..536	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900