DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-zeta and pigrl4.2

DIOPT Version :9

Sequence 1:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001293038.1	Gene:	pigrl4.2 / 105665605	ZFINID:	ZDB-GENE-150409-10	Length:	240	Species:	Danio rerio

Alignment Length:	211	Identity:	48/211 - (22%)
Similarity:	76/211 - (36%)	Gaps:	67/211 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 ENVTVP--------------AGRNVKLGCSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISV 170
            |.:|:|              ...|..|||||....::...|              .||..|
Zfish    32 ETITIPCLYDNKYKLNKKYWCNGNTWLGCSVVAYANHTGKW--------------TITDYP---- 78

  Fly   171 THDKHDRHRTWYLHINNVHEEDRGRYMC--QINTVTAKTQFGYLNVVVPPNIDDSLSSSDVIVRE 233
                  .|..:.:.:||....|.|.|.|  :|:.....:::.||.|...|::  |:.||.|...:
Zfish    79 ------DHNMFTVTLNNSTSSDSGHYWCAVEIDHHVDNSKYLYLTVQKAPDV--SVLSSSVSGHK 135

  Fly   234 GANISLRC-RASGSPRPIIKWKRDD--------------NSRIAINKNHIVNEWEGD---TLEIT 280
            |.::|:|| ..|.....:.:|.|.|              ||.:.|:.       :|:   |:.:|
Zfish   136 GDDVSVRCFYRSAYQNKLKQWCRIDDLTCFREKKTDTSQNSSVQISD-------DGESSFTVLMT 193

  Fly   281 RISRLDMGAYLCIASN 296
            .:...|.|.|.|...|
Zfish   194 GLRLSDSGWYFCSVGN 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	24/111 (22%)
		Ig	130..200	CDD:143165	16/71 (23%)
		I-set	226..310	CDD:254352	22/89 (25%)
		IGc2	233..298	CDD:197706	19/82 (23%)
		Ig	313..410	CDD:299845
		IG_like	325..410	CDD:214653
pigrl4.2	NP_001293038.1	IG_like	26..118	CDD:214653	23/109 (21%)
		Ig_pIgR	30..117	CDD:143193	22/108 (20%)
		Ig	133..217	CDD:299845	19/84 (23%)
		IG_like	136..218	CDD:214653	19/81 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12510
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910