Protein Alignment Try29F and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 106/274 - (38%)
• Similarity: 139/274 - (50%)
• Gaps: 38/274 - (13%)

  Fly    19 IGGIL--------------LVNLSLGATVRRPRLDGRIVGGQVANIKDIPYQVSLQRSY-HFCGG 68
            :||.|              :|:|.......|| |..||||||.......|:|.|:...: |.|||
Human   182 LGGFLEEAWQPRNNCTSGQVVSLRCSECGARP-LASRIVGGQSVAPGRWPWQASVALGFRHTCGG 245

  Fly    69 SLIAQGWVLTAAHCTEGSAILLSKVRIGSSRTSVG-----------GQLVGIKRVHRHPKFDAYT 122
            |::|..||:|||||.....:    .|:.|.|...|           |.||  :|:..||.:.|..
Human   246 SVLAPRWVVTAAHCMHSFRL----ARLSSWRVHAGLVSHSAVRPHQGALV--ERIIPHPLYSAQN 304

  Fly   123 IDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGWGNTQ-SAQETSAVLRSVTVPKV 186
            .|:|.:||.|:.....:.|...|.||.::.....|:...|||||:|. |...:|.:|:...||..
Human   305 HDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLF 369

  Fly   187 SQTQCTEAYGNFGSITDRMLCAGLPEGGKDACQGDSGGPLAA-DGVLW---GVVSWGYGCARPNY 247
            |...|..:....|::|.||||||..:|..|||||||||||.. ||..|   ||||||.|||.||:
Human   370 STQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNH 434

  Fly   248 PGVYSRVSAVRDWI 261
            ||||::|:...|||
Human   435 PGVYAKVAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	97/237 (41%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	5/30 (17%)
		Tryp_SPc	217..448	CDD:214473	96/236 (41%)