DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Try29F and Prss36

DIOPT Version :9

Sequence 1:	NP_001285772.1	Gene:	Try29F / 34226	FlyBaseID:	FBgn0015316	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	288	Identity:	95/288 - (32%)
Similarity:	128/288 - (44%)	Gaps:	46/288 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 HLFIGGILLV----------------------NLSLGATVRRPRLDGRIVGGQVANIKDIPYQVS 58
            |||:..:::|                      :|..|    ||....|||||..|:....|:|||
Mouse     4 HLFLPVVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCG----RPEPSSRIVGGSDAHPGTWPWQVS 64

  Fly    59 L-QRSYHFCGGSLIAQGWVLTAAHC--TEGSAILLSKVRIGSSRTSVGGQLVG-----IKRVHRH 115
            | |...|.|||||||..|||:||||  |.|:.....::.:.....|..|.|.|     :..:...
Mouse    65 LHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIP 129

  Fly   116 PKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGWGNTQSAQETSA--VL 178
            ..:....:..|.:||.|...:....:...|.||......|.||....:|||:.|.|.....  ||
Mouse   130 DNYSTVELGADLALLRLASPAKLGPSVRPVCLPRASHLFAHGTACWATGWGDVQEAVPLPLPWVL 194

  Fly   179 RSVTVPKVSQTQCTEAYGNFG------SITDRMLCAGLPEGGKDACQGDSGGPLAA-DGVLW--- 233
            :.|.:..:.:..|...|...|      .:...|||||.|.|.:|.|||||||||.. ||..|
Mouse   195 QEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLA 259

  Fly   234 GVVSWGYGCARPNYPGVYSRVSAVRDWI 261
            |:.|:|:||.|.|.|||::.|:....||
Mouse   260 GITSFGFGCGRRNRPGVFTAVAPYESWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_001285772.1	Tryp_SPc	41..261	CDD:214473	85/239 (36%)
Try29F	NP_001285772.1	Tryp_SPc	42..264	CDD:238113	86/240 (36%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	86/240 (36%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839456
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930