DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Try29F and prss1

DIOPT Version :9

Sequence 1:	NP_001285772.1	Gene:	Try29F / 34226	FlyBaseID:	FBgn0015316	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_571783.2	Gene:	prss1 / 65223	ZFINID:	ZDB-GENE-010131-7	Length:	247	Species:	Danio rerio

Alignment Length:	227	Identity:	97/227 - (42%)
Similarity:	130/227 - (57%)	Gaps:	12/227 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DGRIVGGQVANIKDIPYQVSLQRSYHFCGGSLIAQGWVLTAAHCTEGSAILLSKVRIGSSRTSV- 102
            |.:||||.......:||||||...|||||||||:..||::||||.:...    :||:|.....|
Zfish    22 DDKIVGGYECTKNGVPYQVSLNSGYHFCGGSLISNLWVVSAAHCYKSRV----QVRLGEHNIDVT 82

  Fly   103 --GGQLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGW 165
              ..|.:..::|.|||.:::.|:|.|..|::|...:..|.....|.||...|  :.||..|:|||
Zfish    83 EGTEQFINSEKVIRHPSYNSNTLDNDVMLIKLSSSAQINSYVKTVSLPSSCA--SSGTSCLISGW 145

  Fly   166 GN-TQSAQETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEGGKDACQGDSGGPLAAD 229
            || :.|.....:.|..:..|.:|.:.|..||.  |.|:..|.|||..|||||:||||||||:..:
Zfish   146 GNMSASGSNYPSRLMCLNAPILSDSTCRNAYP--GQISSNMFCAGFMEGGKDSCQGDSGGPVVCN 208

  Fly   230 GVLWGVVSWGYGCARPNYPGVYSRVSAVRDWI 261
            ..|.|:||||||||:.|.||||::|.....||
Zfish   209 NQLQGIVSWGYGCAQRNKPGVYAKVCNFTTWI 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_001285772.1	Tryp_SPc	41..261	CDD:214473	94/223 (42%)
Try29F	NP_001285772.1	Tryp_SPc	42..264	CDD:238113	96/224 (43%)
prss1	NP_571783.2	Tryp_SPc	24..240	CDD:214473	94/223 (42%)
prss1	NP_571783.2	Tryp_SPc	25..243	CDD:238113	96/224 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3303
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134055
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	1	1.000	-	-		FOG0000102
OrthoInspector	1	1.000	-	-		mtm6438
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10390
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.750