DRSC/TRiP Functional Genomics Resources

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Protein Alignment Try29F and TMPRSS3

DIOPT Version :10

Sequence 1:NP_523518.2 Gene:Try29F / 34226 FlyBaseID:FBgn0015316 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_076927.1 Gene:TMPRSS3 / 64699 HGNCID:11877 Length:454 Species:Homo sapiens


Alignment Length:259 Identity:95/259 - (36%)
Similarity:130/259 - (50%) Gaps:34/259 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LVNLSLGATVRRPRLDGRIVGGQVANIKDIPYQVSLQ-RSYHFCGGSLIAQGWVLTAAHCTEGSA 87
            :|.|...|...|.....|||||.::.:...|:|.||| :.||.||||:|...|::|||||...  
Human   199 VVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYD-- 261

  Fly    88 ILLSK---VRIGSSRTSVGGQLVG----------IKRVHRHPKFDAYTIDFDFSLLELEEYSAKN 139
            :.|.|   :::|         ||.          ::::..|.|:....:..|.:|::|......|
Human   262 LYLPKSWTIQVG---------LVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFN 317

  Fly   140 VTQAFVGLPEQDADIADGTPVLVSGWGNTQ-SAQETSAVLRSVTVPKVSQTQCT--EAYGNFGSI 201
            .....|.||..:.:..||.....||||.|: .|.:.|.||....||.:|...|.  :.||  |.|
Human   318 EMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYG--GII 380

  Fly   202 TDRMLCAGLPEGGKDACQGDSGGPLAA-DGVLW---GVVSWGYGCARPNYPGVYSRVSAVRDWI 261
            :..|||||...||.|:|||||||||.. :..||   |..|:|.|||..|.||||:||::..|||
Human   381 SPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Try29FNP_523518.2 Tryp_SPc 42..264 CDD:238113 90/241 (37%)
TMPRSS3NP_076927.1 LDLa 74..107 CDD:238060
SRCR_2 112..210 CDD:464747 3/10 (30%)
Tryp_SPc 216..444 CDD:214473 89/240 (37%)
Blue background indicates that the domain is not in the aligned region.

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