DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Try29F and Prss21

DIOPT Version :9

Sequence 1:	NP_001285772.1	Gene:	Try29F / 34226	FlyBaseID:	FBgn0015316	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_065233.2	Gene:	Prss21 / 57256	MGIID:	1916698	Length:	324	Species:	Mus musculus

Alignment Length:	303	Identity:	96/303 - (31%)
Similarity:	135/303 - (44%)	Gaps:	54/303 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IGLTGMAKTILHLFI----GGILLVNLSLGATVRRPRLD---------------GRIVGGQVANI 50
            :|..|  ||::.|.:    ..:.|.:..|.....:|.|.               .|||||..|.:
Mouse     1 MGARG--KTLVPLLVVVATAAMALQSTYLQVDPEKPELQEPDLLSGPCGHRTIPSRIVGGDDAEL 63

  Fly    51 KDIPYQVSLQ-RSYHFCGGSLIAQGWVLTAAHCTE---------------GSAILLSKVRIGSSR 99
            ...|:|.||: ...|.||.:|:.:.||||||||.:               .|...|..::..|:|
Mouse    64 GRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHCFQKDNDPFDWTVQFGELTSRPSLWNLQAYSNR 128

  Fly   100 TSVGGQLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSG 164
            ..:....:..|...::|.        |.:||:|......|.....:.|........:.|...|:|
Mouse   129 YQIEDIFLSPKYSEQYPN--------DIALLKLSSPVTYNNFIQPICLLNSTYKFENRTDCWVTG 185

  Fly   165 WG--NTQSAQETSAVLRSVTVPKVSQTQCTEAY--GNF-GSITDRMLCAGLPEGGKDACQGDSGG 224
            ||  ....:..:...|:.|.|..::.:.|...|  .:| .:|...|:|||.||||||||.|||||
Mouse   186 WGAIGEDESLPSPNTLQEVQVAIINNSMCNHMYKKPDFRTNIWGDMVCAGTPEGGKDACFGDSGG 250

  Fly   225 PLAAD-GVLW---GVVSWGYGCARPNYPGVYSRVSAVRDWISS 263
            |||.| ..:|   ||||||.||.|||.||||:.:|...:||.|
Mouse   251 PLACDQDTVWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWIQS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_001285772.1	Tryp_SPc	41..261	CDD:214473	84/244 (34%)
Try29F	NP_001285772.1	Tryp_SPc	42..264	CDD:238113	86/247 (35%)
Prss21	NP_065233.2	Tryp_SPc	54..291	CDD:214473	84/244 (34%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	86/247 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810