Protein Alignment Try29F and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 103/279 - (36%)
• Similarity: 156/279 - (55%)
• Gaps: 37/279 - (13%)

  Fly     1 MRSSIG--LTGMAKTILHLFIGGILLVNLSLGATVRRPRLDGRIVGGQVANIKDIPYQVSLQ-RS 62
            ||:|.|  |:| :...||.         |:.|.:::.|    |:||.:.|::...|:|||:| ..
Human   176 MRNSSGPCLSG-SLVSLHC---------LACGKSLKTP----RVVGVEEASVDSWPWQVSIQYDK 226

  Fly    63 YHFCGGSLIAQGWVLTAAHC-TEGSAILLSKVRIGSSR-----TSVGGQLVGIKRVHRHPKFDAY 121
            .|.||||::...|||||||| .:.:.:...|||.||.:     :....:::.|:....:||
Human   227 QHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPK---- 287

  Fly   122 TIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGWGNT-QSAQETSAVLRSVTVPK 185
              |.|.:|::|:.....:.|...:.||..|.::...||:.:.|||.| |:..:.|.:|...:|..
Human   288 --DNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQV 350

  Fly   186 VSQTQCT--EAYGNFGSITDRMLCAGLPEGGKDACQGDSGGPLAADGVLW---GVVSWGYGCARP 245
            :..|:|.  :||.  |.:|::|:|||:||||.|.|||||||||......|   |:|||||||..|
Human   351 IDSTRCNADDAYQ--GEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGP 413

  Fly   246 NYPGVYSRVSAVRDWISSV 264
            :.||||::|||..:||.:|
Human   414 STPGVYTKVSAYLNWIYNV 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	90/234 (38%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	9/30 (30%)
		Tryp_SPc	204..429	CDD:214473	89/232 (38%)