Protein Alignment Try29F and PRSS1

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 97/229 - (42%)
• Similarity: 131/229 - (57%)
• Gaps: 12/229 - (5%)

  Fly    39 DGRIVGGQVANIKDIPYQVSLQRSYHFCGGSLIAQGWVLTAAHCTEGSAILLSKVRIGSSRTSV- 102
            |.:||||.......:||||||...|||||||||.:.||::|.||.:...    :||:|.....|
Human    21 DDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRI----QVRLGEHNIEVL 81

  Fly   103 --GGQLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGW 165
              ..|.:...::.|||::|..|::.|..|::|...:..|...:.:.||  .|..|.||..|:|||
Human    82 EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLP--TAPPATGTKCLISGW 144

  Fly   166 GNT-QSAQETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEGGKDACQGDSGGPLAAD 229
            ||| .|..:....|:.:..|.:||.:|..:|.  |.||..|.|.|..|||||:||||||||:..:
Human   145 GNTASSGADYPDELQCLDAPVLSQAKCEASYP--GKITSNMFCVGFLEGGKDSCQGDSGGPVVCN 207

  Fly   230 GVLWGVVSWGYGCARPNYPGVYSRVSAVRDWISS 263
            |.|.||||||.|||:.|.||||::|.....||.:
Human   208 GQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKN 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	96/226 (42%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	94/223 (42%)