DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Try29F and Prss53

DIOPT Version :9

Sequence 1:	NP_001285772.1	Gene:	Try29F / 34226	FlyBaseID:	FBgn0015316	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	78/312 - (25%)
Similarity:	125/312 - (40%)	Gaps:	77/312 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LFIGGILLVNLSLGATVR----------RPRLDGRIVGGQVANIKDIPYQVSLQR-SYHFCGGSL 70
            |.:|.::::. .|.|..|          .|: :|..:.|      :.|:|.|::| ..|.|.|||
  Rat    10 LIVGAVIVIE-GLQAAQRACGQRGPGPPEPQ-EGNTLPG------EWPWQASVRRQGVHICSGSL 66

  Fly    71 IAQGWVLTAAHCTE--GSAILLS-KVRIGSSR---TSVGGQLVGIKRVHRHPKFDAYTIDFDFSL 129
            :|..||||||||.|  .:|.|.| .|.:||.:   .|.|.:.||:..:.....::.|:...|.:|
  Rat    67 VADTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLAL 131

  Fly   130 LELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGW----------------------------- 165
            |:|    ...:....:.||:.......|.....:||
  Rat   132 LQL----THPIVHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLAL 192

  Fly   166 --------GNTQSAQETSAVLRSVTVPKVSQTQCTEAYGNF------GSITDRMLCAGLPEGGKD 216
                    .:|.|....|..||::.:..:|:..|...|...      ......|||.|...|.:.
  Rat   193 CSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPARSGMLCGGAQPGVQG 257

  Fly   217 ACQGDSGGPLAA---DG--VLWGVVSWGYGCARPNYPGVYSRVSAVRDWISS 263
            .||||||||:..   ||  |..|::|:...||:.:.|.:.:.::|...|:.:
  Rat   258 PCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWLQA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_001285772.1	Tryp_SPc	41..261	CDD:214473	70/274 (26%)
Try29F	NP_001285772.1	Tryp_SPc	42..264	CDD:238113	71/277 (26%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	71/275 (26%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030