DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Try29F and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001285772.1	Gene:	Try29F / 34226	FlyBaseID:	FBgn0015316	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	93/245 - (37%)
Similarity:	130/245 - (53%)	Gaps:	30/245 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RIVGGQVANIKDIPYQVSLQR-SYHFCGGSLIAQGWVLTAAHCTEGSA----------ILLSKVR 94
            ::.|||.|...:.|:|.|||: :.|.||.:||:..|::|||||...||          .||||.:
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFLLSKPQ 250

  Fly    95 IGSSRTSVGGQLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTP 159
            ...:..|:        .:|.:..:.|:..|.....|........|:.:|.  |||........:.
  Rat   251 AQRAVKSI--------VIHENYSYPAHNNDIAVVRLSSPVLYENNIRRAC--LPEATQKFPPNSD 305

  Fly   160 VLVSGWGNTQSAQETSAVLRSVTVPKVSQTQCT--EAYGNFGSITDRMLCAGLPEGGKDACQGDS 222
            |:|:|||..:|..::..:|:...|..:....|.  :|||  |.||..|||||..||..|||||||
  Rat   306 VVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYG--GVITPGMLCAGFLEGRVDACQGDS 368

  Fly   223 GGPLAAD---GV--LWGVVSWGYGCARPNYPGVYSRVSAVRDWISSVSGI 267
            ||||.::   |:  |.|:||||..||.||.||||:||:..||||||.:|:
  Rat   369 GGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSKTGL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_001285772.1	Tryp_SPc	41..261	CDD:214473	88/237 (37%)
Try29F	NP_001285772.1	Tryp_SPc	42..264	CDD:238113	91/239 (38%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	88/237 (37%)
		Tryp_SPc	187..415	CDD:238113	91/239 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920