DRSC/TRiP Functional Genomics Resources

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Protein Alignment Try29F and KLK3

DIOPT Version :9

Sequence 1:NP_001285772.1 Gene:Try29F / 34226 FlyBaseID:FBgn0015316 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_001639.1 Gene:KLK3 / 354 HGNCID:6364 Length:261 Species:Homo sapiens


Alignment Length:255 Identity:86/255 - (33%)
Similarity:118/255 - (46%) Gaps:21/255 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 ILLVNLSLGATVRRPRLDGRIVGGQVANIKDIPYQVSL-QRSYHFCGGSLIAQGWVLTAAHCTEG 85
            ::.:.||:......|.:..|||||........|:||.: .|....|||.|:...||||||||...
Human     5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN 69

  Fly    86 -SAILLSKVRIGSSRTSVGGQLVGIKRVHRHPKFDAYTI-----------DFDFSLLELEEYSAK 138
             |.|||.:..:.....:  ||:..:.....||.:|...:           ..|..||.|.|.:..
Human    70 KSVILLGRHSLFHPEDT--GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132

  Fly   139 NVTQAFVGLPEQDADIADGTPVLVSGWGNTQSAQ-ETSAVLRSVTVPKVSQTQCTEAYGNFGSIT 202
            ......:.||.|:.  |.||....||||:.:..: .|...|:.|.:..:|...|.:.:..  .:|
Human   133 TDAVKVMDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ--KVT 193

  Fly   203 DRMLCAGLPEGGKDACQGDSGGPLAADGVLWGVVSWG-YGCARPNYPGVYSRVSAVRDWI 261
            ..|||||...|||..|.|||||||..:|||.|:.||| ..||.|..|.:|::|...|.||
Human   194 KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Try29FNP_001285772.1 Tryp_SPc 41..261 CDD:214473 81/234 (35%)
Tryp_SPc 42..264 CDD:238113 82/235 (35%)
KLK3NP_001639.1 Tryp_SPc 25..256 CDD:238113 82/235 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8511
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.920

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