Protein Alignment Try29F and PRSS53

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 83/333 - (24%)
• Similarity: 121/333 - (36%)
• Gaps: 110/333 - (33%)

  Fly    20 GGILLVNLSLGATVRRPRL------------------DGRIVGGQVANIKDIPYQVSLQR-SYHF 65
            |.:||:   .||||....|                  :|..|.|      :.|:|.|::| ..|.
Human     6 GPVLLI---AGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPG------EWPWQASVRRQGAHI 61

  Fly    66 CGGSLIAQGWVLTAAHCTEGSA---------ILLSKVRIGSSRTSVGGQLVGIKRVHRHPKFDAY 121
            |.|||:|..||||||||.|.:|         :|.|..|.|   .|.|.:.||:..:.....::.|
Human    62 CSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREG---LSPGAEEVGVAALQLPRAYNHY 123

  Fly   122 TIDFDFSLLELEEYSAKNVTQAFVGLPEQDADIADGTPVLVSGWGNTQSAQETS----------- 175
            :...|.:||:|    |...|...:.||:.......|.....:||.     |:||
Human   124 SQGSDLALLQL----AHPTTHTPLCLPQPAHRFPFGASCWATGWD-----QDTSDGKCWPRLKLG 179

  Fly   176 ---------------------------------------AVLRSVTVPKVSQTQCTEAYGNF--- 198
                                                   ..||::.:..:|:..|...|...
Human   180 EALCLPSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLHQR 244

  Fly   199 ---GSITDRMLCAGLPEGGKDACQGDSGGP---LAADG--VLWGVVSWGYGCARPNYPGVYSRVS 255
               ......|||.|...|.:..||||||||   |..||  |..|::|:...||:.:.|.:.:..:
Human   245 HLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTA 309

  Fly   256 AVRDWISS 263
            |...|:.:
Human   310 AHSSWLQA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	74/293 (25%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	74/291 (25%)
		Tryp_SPc	359..>512	CDD:473915