Protein Alignment Try29F and HGFAC

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 91/251 - (36%)
• Similarity: 132/251 - (52%)
• Gaps: 30/251 - (11%)

  Fly    34 RRPRLDGRIVGGQVANIKDIPYQVSLQRSYHFCGGSLIAQGWVLTAAHCTEGSAILLS-KVRIGS 97
            :|..|..||:||..:.....|:..::.....||.|||:...||::||||...|....| .|.:|.
Human   407 KRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQ 471

  Fly    98 ---SRTSVGGQLVGIKRVHRHPKFDAYTI-------DFDFSLLELEEYSAKNVTQA-FVG---LP 148
               :||:...|..||:      |:..||:       |.|..|:.|::...:..|:: ||.   ||
Human   472 HFFNRTTDVTQTFGIE------KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 530

  Fly   149 EQDADIADGTPVLVSGWGN-TQSAQETSAVLRSVTVPKVSQTQCT--EAYGNFGSITDRMLCAGL 210
            |..:....|....::|||: .::....|:.||...||.|:..:|:  |.||  ..|:..|||||.
Human   531 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYG--ADISPNMLCAGY 593

  Fly   211 PEGGKDACQGDSGGPLAAD--GV--LWGVVSWGYGCARPNYPGVYSRVSAVRDWIS 262
            .:...||||||||||||.:  ||  |:|::|||.||.|.:.||||:||:...|||:
Human   594 FDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	88/243 (36%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	88/243 (36%)