Protein Alignment Try29F and GZMK

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 86/258 - (33%)
• Similarity: 128/258 - (49%)
• Gaps: 34/258 - (13%)

  Fly    27 LSLGATVRRPRLDGRIVGGQVANIKDIPYQVSLQ-RSYHFCGGSLIAQGWVLTAAHC----TEGS 86
            |.:||.:.....:..|:||:..:....|:..|:| ..:|.|||.||...||||||||    |:|.
Human    12 LIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQ 76

  Fly    87 AILLSKVRIGS---SRTSVGGQLVGIK------RVHRHPKFDAYTIDFDFSLLELEEYSA--KNV 140
            :   ..|.:|:   |:.....|.:.||      ||...|:.:      |..|::|:..:.  |:|
Human    77 S---PTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSN------DIMLVKLQTAAKLNKHV 132

  Fly   141 TQAFVGLPEQDADIADGTPVLVSGWGNTQ-SAQETSAVLRSVTVPKVSQTQC-TEAYGNFGS--I 201
            ....:   .....:..||...|:|||.|. .:...|..||.|||..:|:..| :::|.| |.  |
Human   133 KMLHI---RSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYN-GDPFI 193

  Fly   202 TDRMLCAGLPEGGKDACQGDSGGPLAADGVLWGVVSWGYGCARPNYPGVYSRVS-AVRDWISS 263
            |..|:|||..:|.||:|:|||||||...||...:||.|:.|.....||:|:.:: ..:.||.|
Human   194 TKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKS 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	83/243 (34%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	83/243 (34%)