DRSC/TRiP Functional Genomics Resources

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Protein Alignment Try29F and GZMB

DIOPT Version :9

Sequence 1:NP_001285772.1 Gene:Try29F / 34226 FlyBaseID:FBgn0015316 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_004122.2 Gene:GZMB / 3002 HGNCID:4709 Length:247 Species:Homo sapiens


Alignment Length:243 Identity:81/243 - (33%)
Similarity:112/243 - (46%) Gaps:15/243 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 LSLGATVRRPRLD-GRIVGGQVANIKDIPYQVSL----QRSYHFCGGSLIAQGWVLTAAHCTEGS 86
            |.|.|.:..||.| |.|:||..|.....||...|    |:|...|||.||...:|||||||. ||
Human     5 LLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-GS 68

  Fly    87 AILLSKVRIGS---SRTSVGGQLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVGLP 148
            :|   .|.:|:   .......|.:.:||...||.::......|..||:||..:.:......:.||
Human    69 SI---NVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLP 130

  Fly   149 EQDADIADGTPVLVSGWGNTQSAQETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEG 213
            ...|.:..|....|:|||.|....:.|..|:.|.:......:|.....::...|.. ||.|.||.
Human   131 SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE-LCVGDPEI 194

  Fly   214 GKDACQGDSGGPLAADGVLWGVVSWGYGCARPNYPGVYSRVSAVRDWI 261
            .|.:.:|||||||..:.|..|:||:|.....|  |...::||:...||
Human   195 KKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVHWI 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Try29FNP_001285772.1 Tryp_SPc 41..261 CDD:214473 72/226 (32%)
Tryp_SPc 42..264 CDD:238113 74/227 (33%)
GZMBNP_004122.2 Tryp_SPc 20..240 CDD:214473 72/226 (32%)
Tryp_SPc 21..243 CDD:238113 74/227 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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