DRSC/TRiP Functional Genomics Resources

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Protein Alignment Try29F and KLK5

DIOPT Version :9

Sequence 1:NP_001285772.1 Gene:Try29F / 34226 FlyBaseID:FBgn0015316 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_001070959.1 Gene:KLK5 / 25818 HGNCID:6366 Length:293 Species:Homo sapiens


Alignment Length:251 Identity:91/251 - (36%)
Similarity:127/251 - (50%) Gaps:27/251 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 NLSLGA----TVRRPRLDGRIVGGQVANIKDIPYQVS--LQRSYHFCGGSLIAQGWVLTAAHCTE 84
            |..|||    ..|......||:.|...::...|:|.:  |:.:..:||..|:...|:||||||.:
Human    47 NQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK 111

  Fly    85 GSAILLSKVRIGSSRTS----VGGQLV-GIKRVHRHPKFDAYTIDFDFSLLELEE--YSAKNVTQ 142
                .:.:||:|....|    .|.|:. |:|.: .||.:.......|..|::|..  ...|:|..
Human   112 ----KVFRVRLGHYSLSPVYESGQQMFQGVKSI-PHPGYSHPGHSNDLMLIKLNRRIRPTKDVRP 171

  Fly   143 AFVGLPEQDADIADGTPVLVSGWGNTQSAQ-ETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRML 206
            ..|......|    ||..||||||.|:|.| ....||:.:.:..:||.:|.:||..  .|.|.|.
Human   172 INVSSHCPSA----GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR--QIDDTMF 230

  Fly   207 CAGLPEGGKDACQGDSGGPLAADGVLWGVVSWG-YGCARPNYPGVYSRVSAVRDWI 261
            ||| .:.|:|:||||||||:..:|.|.|:|||| |.|||||.||||:.:.....||
Human   231 CAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Try29FNP_001285772.1 Tryp_SPc 41..261 CDD:214473 84/230 (37%)
Tryp_SPc 42..264 CDD:238113 85/231 (37%)
KLK5NP_001070959.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 37..68 6/20 (30%)
Tryp_SPc 66..285 CDD:214473 84/230 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8511
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.910

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