Protein Alignment Try29F and KLK8

DIOPT Version :10

• Sequence 1: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 85/242 - (35%)
• Similarity: 118/242 - (48%)
• Gaps: 28/242 - (11%)

  Fly    39 DGRIVGGQVANIKDIPYQVSL-QRSYHFCGGSLIAQGWVLTAAHCTEGSAILLSKVRIGS-SRTS 101
            :.:::||........|:|.:| |.....|||.|:...||||||||.:..    ..||:|. |..:
Human    75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK----YTVRLGDHSLQN 135

  Fly   102 VGG--QLVGIKRVHRHPKFDAYTID---FDFSLLELEEYSAKNVTQAFVGLPEQDADIAD----- 156
            ..|  |.:.:.:...||.:::..::   .|..||:|.:       ||.:|...:...:||
Human   136 KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRD-------QASLGSKVKPISLADHCTQP 193

  Fly   157 GTPVLVSGWGNTQSAQET-SAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEGGKDACQG 220
            |....|||||...|.:|. ...|....|....|.:|.:||.  |.|||.|:|||..:|. |.|||
Human   194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP--GQITDGMVCAGSSKGA-DTCQG 255

  Fly   221 DSGGPLAADGVLWGVVSWGYG-CARPNYPGVYSRVSAVRDWISSVSG 266
            ||||||..||.|.|:.|||.. |.|.:.||||:.:....|||..:.|
Human   256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	84/235 (36%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	82/233 (35%)