DRSC/TRiP Functional Genomics Resources

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Protein Alignment Try29F and KLK11

DIOPT Version :9

Sequence 1:NP_001285772.1 Gene:Try29F / 34226 FlyBaseID:FBgn0015316 Length:267 Species:Drosophila melanogaster
Sequence 2:XP_011524671.1 Gene:KLK11 / 11012 HGNCID:6359 Length:307 Species:Homo sapiens


Alignment Length:306 Identity:97/306 - (31%)
Similarity:136/306 - (44%) Gaps:65/306 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 SSIGLTG-----------MAKTILHLFIGGILLVNLSLGATVRRPRLDGRIVGGQVANIKDI--- 53
            |..|||.           .|..||.|     :|:.|:.|           :|||:...||..   
Human    13 SGRGLTAAKEPGARSSPLQAMRILQL-----ILLALATG-----------LVGGETRIIKGFECK 61

  Fly    54 ----PYQVSL-QRSYHFCGGSLIAQGWVLTAAHCTEGSAILLSKVRIGSSRTSVGGQLVGIKR-- 111
                |:|.:| :::...||.:|||..|:||||||.:....|.|...:....:|....|..:.|  
Human    62 PHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYI 126

  Fly   112 VH----------------------RHPKFDAYTIDFDF--SLLELEEYSAKNVTQAFVGLPEQDA 152
            ||                      .||.|:....:.|.  .::.::..|..::|.|...|.....
Human   127 VHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSR 191

  Fly   153 DIADGTPVLVSGWGNTQSAQ-ETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEGGKD 216
            .:..||..|:||||:|.|.| .....||...:..:...:|..||.  |:|||.|:||.:.|||||
Human   192 CVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYP--GNITDTMVCASVQEGGKD 254

  Fly   217 ACQGDSGGPLAADGVLWGVVSWGYG-CARPNYPGVYSRVSAVRDWI 261
            :|||||||||..:..|.|::|||.. ||....||||::|....|||
Human   255 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWI 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Try29FNP_001285772.1 Tryp_SPc 41..261 CDD:214473 84/255 (33%)
Tryp_SPc 42..264 CDD:238113 86/256 (34%)
KLK11XP_011524671.1 Tryp_SPc 53..300 CDD:214473 81/248 (33%)
Tryp_SPc 54..303 CDD:238113 83/249 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8511
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.920

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