DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alien and FUS12

DIOPT Version :9

Sequence 1:	NP_001260276.1	Gene:	alien / 34225	FlyBaseID:	FBgn0013746	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_565632.1	Gene:	FUS12 / 817241	AraportID:	AT2G26990	Length:	439	Species:	Arabidopsis thaliana

Alignment Length:	434	Identity:	258/434 - (59%)
Similarity:	334/434 - (76%)	Gaps:	3/434 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DDEDYGLEYSEDSNSEPDVDLENQYYNSKALKEEEPKAALASFQKVLDLENGEKGEWGFKALKQM 76
            |.||||.|||::...|.|||:||||||||.:.|.||:.||:.|.:|:.:| .||.:||||||||.
plant     6 DMEDYGFEYSDEEQEEQDVDIENQYYNSKGMVETEPEEALSGFAEVVQME-PEKADWGFKALKQT 69

  Fly    77 IKINFRLCNYDEMMVRYKQLLTYIKSAVTRNHSEKSINSILDYI--STSKNMALLQNFYETTLDA 139
            :||.:||..|.|||..|.::|||||||||||:|||.||:|:|::  |.|:|..|||.||:|||.|
plant    70 VKIYYRLGKYKEMMEAYTEMLTYIKSAVTRNYSEKCINNIMDFVSGSASQNTGLLQEFYQTTLKA 134

  Fly   140 LRDAKNDRLWFKTNTKLGKLYFDRSDFTKLQKILKQLHQSCQTDDGEDDLKKGTQLLEIYALEIQ 204
            |.:|||:|||||||.||..::||..::.::.||||:||:|||.:||.||.|||:||||:||:|||
plant   135 LEEAKNERLWFKTNLKLCNIWFDIGEYRRMTKILKELHKSCQKEDGTDDQKKGSQLLEVYAIEIQ 199

  Fly   205 MYTVQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDES 269
            :||..|:|||||.||.::|.||||||||.|||:|||||||||:.|.::|:|.||||||||||||:
plant   200 IYTETKDNKKLKQLYHKALAIKSAIPHPRIMGIIRECGGKMHMAERQWEEAATDFFEAFKNYDEA 264

  Fly   270 GSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVNSYQNNDINEFETILRQH 334
            |:.||..||||||||||||:|.:||||.||||||||||||||||||:.:||.|:|.|||.||:.:
plant   265 GNQRRIQCLKYLVLANMLMESEVNPFDGQEAKPYKNDPEILAMTNLIAAYQRNEIIEFERILKSN 329

  Fly   335 RSNIMADQFIREHIEDLLRNIRTQVLIKLIRPYKNIAIPFIANALNIEPAEVESLLVSCILDDTI 399
            |..||.|.|||.::||||:.:|||||:|||:||..|.||||:..||:...:|..||||.|||..|
plant   330 RRTIMDDPFIRNYMEDLLKKVRTQVLLKLIKPYTKIGIPFISKELNVPETDVTELLVSLILDSRI 394

  Fly   400 KGRIDQVNQVLQLDKINSSASRYNALEKWSNQIQSLQFAVVQKM 443
            .|.||::|:.|......:....:.|::||::|::||...:..::
plant   395 DGHIDEMNRYLLRGDSGNGRKLHKAVDKWNSQLKSLSSNITSRV 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alien	NP_001260276.1	RPN6	104..410	CDD:227488	197/307 (64%)
alien	NP_001260276.1	PCI	310..414	CDD:396121	57/103 (55%)
FUS12	NP_565632.1	RPN6	65..406	CDD:227488	217/340 (64%)
FUS12	NP_565632.1	PCI	305..405	CDD:396121	56/99 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	406	1.000	Domainoid score	I133
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3124
Inparanoid	1	1.050	529	1.000	Inparanoid score	I283
OMA	1	1.010	-	-		QHG53950
OrthoDB	1	1.010	-	-		D1108845at2759
OrthoFinder	1	1.000	-	-		FOG0005623
OrthoInspector	1	1.000	-	-		oto3951
orthoMCL	1	0.900	-	-		OOG6_102225
Panther	1	1.100	-	-	LDO	PTHR10678
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4026
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980