Protein Alignment alien and rpn-6.2

DIOPT Version :10

• Sequence 1: NP_523517.1
• Gene: alien / 34225
• FlyBaseID: FBgn0013746
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_001254972.1
• Gene: rpn-6.2 / 176273
• WormBaseID: WBGene00010309
• Length: 416
• Species: Caenorhabditis elegans
• Alignment Length: 391
• Identity: 88/391 - (22%)
• Similarity: 175/391 - (44%)
• Gaps: 60/391 - (15%)

  Fly    51 LASFQKVLDLENGEKGEWGFKALKQMIKINFRLCNYDEMMVRYKQLLTYIKSAVTRNHSEKSINS 115
            |.:.|..:..:..:..|...|..:.:|      .:|...:.:.|. :|.|::.|      :||.|
 Worm     8 LKAVQSEVSAQTAKSSEAEVKRCEDLI------LSYSRQLAKEKD-ITGIRTLV------ESIRS 59

  Fly   116 ILDYISTSKNMALLQNFYE--TTLD-----ALRDAKNDRL--------WFKTN----------TK 155
            ..|.:..::...|:::..|  .|:|     ||...|.:::        |..:|          .:
 Worm    60 FYDLVGKARASKLIRDIVEHALTIDQGVGPALDHGKKEKIDLLTNCIGWATSNKREFLRRSLQAR 124

  Fly   156 LGKLYFDRSDFTKLQKILKQLHQSCQTDDGEDDLKK--GTQLLEIYALEIQMYTVQKNN--KKLK 216
            |.:||.|..|||..||:.:.|.:         :|||  ..:||...::|....:...||  |...
 Worm   125 LIRLYNDIRDFTNAQKLAQDLSK---------ELKKLEDRELLIEVSVEESKSSFNLNNLAKAKT 180

  Fly   217 ALYEQSLHIKSAIPHPLIMGVIRECGGKMH-LREGEFEKAHTDFFEAFKNYDESGSP-RRTTCLK 279
            ||.....:..||...|.:...:....|.:: ..|.:::.:.:.|:|||:.:...|.. ..|:.||
 Worm   181 ALLTAKTNTNSAFASPQLQASVDMQSGVLYSAEERDYKTSFSYFYEAFEGFASIGDKINATSALK 245

  Fly   280 YLVLANMLMK-----SGINPFDSQEAKPYKNDPEILAMTNLVNSYQNNDINEFETILRQHRSNIM 339
            |::|..:::.     :|:  ..::|...|:..|.|:|:.::.::::...:.:|...|.:|:..::
 Worm   246 YMILCKIMLNETEQLAGL--LAAKEIVAYQKSPRIIAIRSMADAFRKRSLKDFVKALAEHKIELV 308

  Fly   340 ADQFIREHIEDLLRNIRTQVLIKLIRPYKNIAIPFIANALNIEPAEVESLLVSCILDDTIKGRID 404
            .|:.:..|.::|.||:..:.:.::|.||..|.:.:||..:.:....||..:...|||..:.|.||
 Worm   309 EDKVVAVHSQNLERNMLEKEISRVIEPYSEIELSYIARVIGMTVPPVERAIARMILDKKLMGSID 373

  Fly   405 Q 405
            |
 Worm   374 Q 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alien	NP_523517.1	RPN6	104..410	CDD:227488	79/338 (23%)
		PCI	310..414	CDD:460195	24/96 (25%)
rpn-6.2	NP_001254972.1	RPN6	14..411	CDD:227488	86/385 (22%)