Protein Alignment alien and Cops2

DIOPT Version :9

• Sequence 1: NP_001260276.1
• Gene: alien / 34225
• FlyBaseID: FBgn0013746
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_001272436.1
• Gene: Cops2 / 12848
• MGIID: 1330276
• Length: 450
• Species: Mus musculus
• Alignment Length: 451
• Identity: 372/451 - (82%)
• Similarity: 406/451 - (90%)
• Gaps: 8/451 - (1%)

  Fly     1 MSDNDDDFMCDDDEDYGLEYSEDSNSEPDVDLENQYYNSKALKEEEPKAALASFQKVLDLENGEK 65
            |||.:|||||||:|||.|||||||||||:|||||||||||||||::|||||:||||||:|| |||
Mouse     1 MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELE-GEK 64

  Fly    66 GEWGFKALKQMIKINFRLCNYDEMMVRYKQLLTYIKSAVTRNHSEKSINSILDYISTSK------ 124
            ||||||||||||||||:|.|:.|||.|||||||||:||||||:||||||||||||||||
Mouse    65 GEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFL 129

  Fly   125 -NMALLQNFYETTLDALRDAKNDRLWFKTNTKLGKLYFDRSDFTKLQKILKQLHQSCQTDDGEDD 188
             .|.|||.||||||:||:|||||||||||||||||||.:|.::.||||||:||||||||||||||
Mouse   130 CQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 194

  Fly   189 LKKGTQLLEIYALEIQMYTVQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFE 253
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
Mouse   195 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFE 259

  Fly   254 KAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVNS 318
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||::
Mouse   260 KAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSA 324

  Fly   319 YQNNDINEFETILRQHRSNIMADQFIREHIEDLLRNIRTQVLIKLIRPYKNIAIPFIANALNIEP 383
            ||||||.|||.||:.:.||||.|.|||||||:||||||||||||||:||..|.||||:..|||:.
Mouse   325 YQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDV 389

  Fly   384 AEVESLLVSCILDDTIKGRIDQVNQVLQLDKINSSASRYNALEKWSNQIQSLQFAVVQKMA 444
            |:||||||.||||:||.||||||||:|:||......:||.||:||:||:.||..|||.|:|
Mouse   390 ADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alien	NP_001260276.1	RPN6	104..410	CDD:227488	267/312 (86%)
		PCI	310..414	CDD:396121	77/103 (75%)
Cops2	NP_001272436.1	RPN6	40..441	CDD:227488	331/401 (83%)
		PCI	316..420	CDD:396121	77/103 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837336
Domainoid	1	1.000	570	1.000	Domainoid score	I233
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3124
Inparanoid	1	1.050	747	1.000	Inparanoid score	I578
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53950
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005623
OrthoInspector	1	1.000	-	-		oto93713
orthoMCL	1	0.900	-	-		OOG6_102225
Panther	1	1.100	-	-	LDO	PTHR10678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R255
SonicParanoid	1	1.000	-	-		X4026
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.930