DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and Cmpk1

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_079923.3	Gene:	Cmpk1 / 66588	MGIID:	1913838	Length:	227	Species:	Mus musculus

Alignment Length:	197	Identity:	48/197 - (24%)
Similarity:	94/197 - (47%)	Gaps:	28/197 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   357 PPIIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTES---FAVKEALAAGD 418
            |.:::|:||||:.|.|.|.:.|. ..|:.|:|.|.|||:     .|.|.:|   ..:::.:..|.
Mouse    34 PLVVFVLGGPGAGKGTQCARIVE-KYGYTHLSAGELLRD-----ERKNPDSQYGELIEKYIKEGK 92

  Fly   419 MAPEKSLNQLLETNLRQL----RDRTGIIVDGYPRNLQQVKYFENKYKQRPP---IILLDCSK-- 474
            :.|.:....||:..:.|.    ..:...::||:|||...::.:......:..   ::..||:.
Mouse    93 IVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEI 157

  Fly   475 -----LQLGR--GRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGDTDSPSVQREFERL 532
                 |:.|:  ||.||...|..:|::.:.|.|.|::.:.:...:::.:|.   |.||...|..:
Mouse   158 CIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDA---SKSVDEVFGEV 219

  Fly   533 IR 534
            ::
Mouse   220 VK 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	43/181 (24%)
		ADK	359..521	CDD:238713	43/180 (24%)
Cmpk1	NP_079923.3	UMP_CMP_kin_fam	36..224	CDD:273576	47/195 (24%)
Cmpk1	NP_079923.3	ADK	36..215	CDD:238713	46/187 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S511
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770