Protein Alignment CG9541 and Ak9

DIOPT Version :10

• Sequence 1: NP_001260273.1
• Gene: CG9541 / 34220
• FlyBaseID: FBgn0032083
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001357742.1
• Gene: Ak9 / 633979
• MGIID: 2685080
• Length: 1879
• Species: Mus musculus
• Alignment Length: 566
• Identity: 103/566 - (18%)
• Similarity: 182/566 - (32%)
• Gaps: 211/566 - (37%)

  Fly    64 DPPKVPV--IFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAM-------GNDMQDFSQ- 118
            :|.|.|.  |.:||..|||| |.|...:.|..|:.||...:.||:..:       |.:.:|.|:
Mouse   954 EPLKAPPLRICLLGPHGSGK-TVCARKLAENFGIFHIQFDEFLQEKMLLKAERKFGPEFEDDSEE 1017

  Fly   119 ----------------------LSSKTVTEVLMLE----------------------------MK 133
                                  .:.|.:.:|.:.|                            :|
Mouse  1018 EQLVKQELEELAAQANVKIEEDTTKKQLPDVQLTEEEEAIKLSLTDNEPLPSEILDSILSEWWLK 1082

  Fly   134 MAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILI-----------------SWR----QSVLQ 177
            ....:..:::.|:||...:.....|:....:..::|                 .|:    :.:.:
Mouse  1083 EPIRSTGFILDGFPRHPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQHKKLER 1147

  Fly   178 KQI--DYGAKLGHVVLSLAKMEL----------------ENFFKNVMPVADYFDQSDMLL----- 219
            |::  |...|:...:::..:.||                |:.|.:  ..|||.|..:.:|
Mouse  1148 KKLIKDLKTKIKEDMVAKRRAELILEREKKRREDGTFRDEDEFSD--EDADYEDDIENILEEEFP 1210

  Fly   220 --------------AVNGERAPTEVYKDFRTAVLDILSTLENQEAVM------NGVTGMGRGIHD 264
                          |...||...|:.:.|.|...:|.|..:..:.|:      ||    .|.:|.
Mouse  1211 KDEEEMSEEDEEQEADATERLRNELGEKFETETNNIQSIQDEFDKVLIPIIMVNG----ARKMHI 1271

  Fly   265 IP--------------GSI------VSVDTA------------------PSQAQQGTQIAEDNDV 291
            :.              .||      ||...|                  |.:..:|..|   ..|
Mouse  1272 VQYVMNMKLKPLVENRESIFEKCYPVSSHLAHKMLSYTYKHMSSFGYWDPVKLSEGETI---KPV 1333

  Fly   292 TNASETAGTVLARDLAI--------ERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAG 348
            .||......|:.|....        |:....|                   :...:|||.:
Mouse  1334 ENAENPLNPVIHRHYIYFLSNKQTKEKFMMNP-------------------IKYIRQPKPK---- 1375

  Fly   349 PDESGSDLPPIIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEA 413
                 :.:|..|.::|.|.|.|.|:. |.:..:.|...:|||..||.:.::.|.:.. |..:...
Mouse  1376 -----ATMPVRIMIVGPPKSGKTTVA-KKLASDYGLRCLSVGDALRGMLNNHPDSEL-SLMLNWH 1433

  Fly   414 LAAGDMAPEKSLNQLLETNLRQ-LRDRTGIIVDGYPRNLQQVKYFE 458
            |..|...|::...|.|:.:|.: :.:..|:::||||....|:...|
Mouse  1434 LHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLE 1479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	ADK	70..230	CDD:238713	43/277 (16%)
		aden_kin_iso1	358..521	CDD:130427	28/102 (27%)
Ak9	NP_001357742.1	ADK	962..1177	CDD:238713	33/215 (15%)
		NMP 2. /evidence=ECO:0000250|UniProtKB:P69441	990..1021		5/30 (17%)
		LID 2. /evidence=ECO:0000250|UniProtKB:P69441	1093..1113		4/19 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1208..1228		1/19 (5%)
		Adenylate kinase 3. /evidence=ECO:0000250|UniProtKB:Q5TCS8	1380..1569		28/102 (27%)
		ADK	1381..1553	CDD:238713	28/101 (28%)
		NMP 3. /evidence=ECO:0000250|UniProtKB:P69441	1409..1440		9/31 (29%)
		LID 3. /evidence=ECO:0000250|UniProtKB:P69441	1504..1518
		Adenylate kinase 1. /evidence=ECO:0000250|UniProtKB:Q5TCS8	32..286
		NK	34..277	CDD:450170
		NMP 1. /evidence=ECO:0000250|UniProtKB:P69441	61..90
		LID 1. /evidence=ECO:0000250|UniProtKB:P69441	161..206
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..211
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..533
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	861..896
		YHS	899..954	CDD:442578	103/566 (18%)
		Adenylate kinase 2. /evidence=ECO:0000250|UniProtKB:Q5TCS8	961..1172		33/211 (16%)