DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak5l

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001017540.1	Gene:	ak5l / 548336	ZFINID:	ZDB-GENE-050410-2	Length:	335	Species:	Danio rerio

Alignment Length:	246	Identity:	66/246 - (26%)
Similarity:	113/246 - (45%)	Gaps:	22/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 RMDGGPNGAVTALK--------TGTTSADDDSGVVVTQQPKLRQAAGPDESGSDLPPIIWVIGGP 366
            ::||||.......:        ....|.:.||.  :|:...|.|.....:.....|.||::||||
Zfish    81 KLDGGPGPGPGPYRRYDRLPPIQAQFSIESDSD--MTESSGLIQEYDVFDPSKPRPHIIFIIGGP 143

  Fly   367 GSNKATLCLKAVGLNPGWAHISVGRLLRN-ITDSAPRANTESFAVKEALAAGDMAPEKSLNQLLE 430
            ||.|.|...| :.|...:.|:|||.:||| :...|| ::.:...:.:.:|.|::||:::..:.|:
Zfish   144 GSGKGTQTAK-IALRYDFEHVSVGEILRNQLLHHAP-SDRKWELIAQIIANGELAPQETTIEELK 206

  Fly   431 TNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSKLQL---------GRGRIDDTV 486
            ....:.:|..|.||||:||.:.|...||.:......:|||.||..||         .:||.||..
Zfish   207 QQFIKKQDAKGFIVDGFPREISQAFTFEEQIGSPDLVILLACSNQQLRQRLEKRASQQGRPDDNS 271

  Fly   487 SSFRRRLELFREQTLPMLKILDTSNRLQIVDGDTDSPSVQREFERLIRNHI 537
            .:..:||:.|:.....:.|.......:..||.|.:...:..:...:::..:
Zfish   272 HAIEKRLDTFKHNINLIAKYYQERGLIVRVDADREEDDIFTDISAIVKERL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	55/172 (32%)
		ADK	359..521	CDD:238713	55/171 (32%)
ak5l	NP_001017540.1	aden_kin_iso1	136..314	CDD:130427	55/179 (31%)
ak5l	NP_001017540.1	ADK	136..310	CDD:238713	55/175 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3899
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810