DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and AK3

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_057366.2	Gene:	AK3 / 50808	HGNCID:	17376	Length:	227	Species:	Homo sapiens

Alignment Length:	197	Identity:	43/197 - (21%)
Similarity:	73/197 - (37%)	Gaps:	50/197 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 VIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAAGDMAPEKSLN 426
            ::|.|||.|.|:..: :..:....|:|.|.|||   |:..|........|..:..|.:.|:..:.
Human    12 IMGAPGSGKGTVSSR-ITTHFELKHLSSGDLLR---DNMLRGTEIGVLAKAFIDQGKLIPDDVMT 72

  Fly   427 QLLETNLRQLRDRTGIIVDGYPRNLQQVKYFENKY---------------KQRPPIILLDCSKLQ 476
            :|....|:.|...:.:: ||:||.|.|.:..:..|               |||     |....:.
Human    73 RLALHELKNLTQYSWLL-DGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQR-----LTARWIH 131

  Fly   477 LGRGRI-------------------------DDTVSSFRRRLELFREQTLPMLKILDTSNRLQIV 516
            ...||:                         ||...:..:||:.:.:||.|:|:.......|:..
Human   132 PASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETF 196

  Fly   517 DG 518
            .|
Human   197 SG 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	43/197 (22%)
		ADK	359..521	CDD:238713	43/197 (22%)
AK3	NP_057366.2	ADK	12..190	CDD:395329	41/187 (22%)
		NMP. /evidence=ECO:0000255\|HAMAP-Rule:MF_03169, ECO:0000269\|Ref.10	37..66		9/31 (29%)
		LID. /evidence=ECO:0000255\|HAMAP-Rule:MF_03169, ECO:0000269\|Ref.10	127..164		2/36 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910