DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak1

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_031746217.1	Gene:	ak1 / 448536	XenbaseID:	XB-GENE-1012039	Length:	566	Species:	Xenopus tropicalis

Alignment Length:	499	Identity:	119/499 - (23%)
Similarity:	211/499 - (42%)	Gaps:	112/499 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 DM-QNAGKIK----FDP----PKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAM 109
            || :::|.|:    |||    ||  :|||:|||||||.|. .|.|....|...:::.|:|::..:
Frog   107 DMTESSGLIQEYDVFDPNRERPK--IIFVIGGPGSGKGTQ-STKMASHFGFICVSVGDILRKQLI 168

  Fly   110 GNDMQD-----FSQLSSK-------TVTEVLMLEMKMAPAAKAYLISGYPRSMRDVVEYSEKIQV 162
            .:...|     .:|:.||       |..|.|..:......|..:::.|:||.:.....:.|:|..
Frog   169 HHASSDRKWELIAQIISKGDLAPPETTIEELKQQFINHQDATGFVVDGFPRDIGQAFTFEEQIGS 233

  Fly   163 VNGVILISWRQSVLQKQIDYGAKL-------GHVVLSLAKMELENFFKNVMPVADYFDQSDMLLA 220
            .:.||.::.....|:::::..|.|       .|.:    ...|..|.:|:..:..|:....::..
Frog   234 PDLVIFLACSSQRLRQRLERRASLHGRPDDNAHAI----DRRLSTFKQNLPLIVKYYQDKGLIAR 294

  Fly   221 VNGERAPTEVYKDFRTAVLDILSTLENQEAVMNGVTGMGRGIHDIPGSIVSVDTAPS----QAQQ 281
            .:.:|....:::|...||..:|        ..||:     |:.:.  |:.|...:.|    :.|:
Frog   295 FDADREEDSIFEDICCAVQGLL--------FPNGL-----GVQEF--SMKSFHASCSEDCKEQQK 344

  Fly   282 GTQIAEDNDVTNASETAGTVLARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQA 346
            ..::.:..              |:|.:.:.:                      :.|...|:..:.
Frog   345 EVELPKQK--------------RELEVPQQE----------------------IEVVFSPEHTEM 373

  Fly   347 AGPDESGSDLPPIIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVK 411
            |...::..    ||:|:|||||.|.|.|.|.|. ..|:.|:|.|.|||....|.........|:.
Frog   374 ADKLKNSK----IIFVVGGPGSGKGTQCEKIVH-QYGYTHLSTGDLLRAEVSSGSERGKHLSAIM 433

  Fly   412 EALAAGDMAP-EKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILL--DCS 473
            |   .|::.| :..|:.|.|..:.:.....|.::|||||.::|.:.||.|.  .||.:||  |..
Frog   434 E---KGELVPLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKI--GPPSLLLYIDAG 493

  Fly   474 K-------LQLGR--GRIDDTVSSFRRRLELFREQTLPMLKILD 508
            .       |:.|.  ||.||..::.::|||.:.:.|.|::.:.:
Frog   494 SDTMVKRLLKRGETSGRADDNEATIKKRLETYYKATEPVIAMYE 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427	42/189 (22%)
		ADK	70..230	CDD:238713	40/178 (22%)
		aden_kin_iso1	358..521	CDD:130427	54/163 (33%)
		ADK	359..521	CDD:238713	54/162 (33%)
ak1	XP_031746217.1	aden_kin_iso1	129..312	CDD:130427	42/189 (22%)
ak1	XP_031746217.1	aden_kin_iso1	378..565	CDD:130427	54/170 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58863
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930