DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak1

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_005168739.1	Gene:	ak1 / 445486	ZFINID:	ZDB-GENE-040822-37	Length:	209	Species:	Danio rerio

Alignment Length:	226	Identity:	56/226 - (24%)
Similarity:	98/226 - (43%)	Gaps:	39/226 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 GTTSADDDSGVVVTQQPKLRQAAGPDESGSDLPPIIWVIGGPGSNKATLCLKAVGLNPGWAHISV 389
            |...:...:..|:....|::.|           .|::|:|||||.|.|.|.|.|. ..|:.|:|.
Zfish     2 GLGCSSKSAAAVMKPDDKIKNA-----------KIVFVVGGPGSGKGTQCEKIVA-KYGYTHLSS 54

  Fly   390 GRLLRNITDSAPRANTESFAVKEALAAGDMAPEKSLNQLLETNLRQLRD--------RTGIIVDG 446
            |.|||....|......:..|:   :..|::.|       |:|.|..::|        ..|.::||
Zfish    55 GDLLRAEVASGSERGKQLQAI---MQKGELVP-------LDTVLDMIKDAMIAKADVSKGYLIDG 109

  Fly   447 YPRNLQQVKYFENKYKQRPPIILLDCS-----KLQLGR----GRIDDTVSSFRRRLELFREQTLP 502
            |||.::|.:.||.|......::.:|..     |..:.|    ||.||...:.::||:|:.:.|.|
Zfish   110 YPREVKQGEEFEKKIGAPALLLYIDAKGETMVKRLMKRGETSGRADDNEETIKKRLDLYYKATEP 174

  Fly   503 MLKILDTSNRLQIVDGDTDSPSVQREFERLI 533
            ::...:....::.::.:.....|....|:.|
Zfish   175 VIAFYEQRGIVRKINSELPVDEVFAIVEKAI 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	49/179 (27%)
		ADK	359..521	CDD:238713	49/178 (28%)
ak1	XP_005168739.1	aden_kin_iso1	21..208	CDD:130427	53/207 (26%)
ak1	XP_005168739.1	ADK	25..197	CDD:238713	49/182 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820