DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak3

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_998295.2	Gene:	ak3 / 406404	ZFINID:	ZDB-GENE-040426-2142	Length:	225	Species:	Danio rerio

Alignment Length:	222	Identity:	53/222 - (23%)
Similarity:	93/222 - (41%)	Gaps:	53/222 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 VIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTES-----FAVKEALAAGDMAP 421
            ::|.|||.|.|:..: :..:.|..|:|.|.:|        |||.|:     ..:|..:..|.:.|
Zfish    11 IMGAPGSGKGTVSSR-IAQSFGLKHLSSGDML--------RANIEAKTDLGLLMKSCIDQGQLVP 66

  Fly   422 EKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIIL----------LDCSKLQ 476
            :..:::|:.::||.| ::|..::||:||.:.|.:..:..|.....|.|          |....:.
Zfish    67 DDVISRLILSSLRGL-EKTSWLLDGFPRTVAQAEALDCVYDVDSVINLDVPFQTIRERLTSRWVH 130

  Fly   477 LGRGRI-------------------------DDTVSSFRRRLELFREQTLPMLKILDTSNRLQIV 516
            |..||:                         ||:..:..|||:.:..||.|:|:...:...|:..
Zfish   131 LPSGRVYNIDFNPPKKPGLDDVTGEPLVQRDDDSPETVSRRLKDYERQTQPVLEYYRSKGVLETF 195

  Fly   517 DG-DTDS--PSVQREFERLIRNHIQRL 540
            .| :|:.  |.|.....|.|..|.|.:
Zfish   196 SGTETNKIWPHVHTFLSRKIPGHKQAM 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	46/199 (23%)
		ADK	359..521	CDD:238713	46/199 (23%)
ak3	NP_998295.2	ADK	8..200	CDD:238713	46/198 (23%)
ak3	NP_998295.2	adk	8..198	CDD:234711	45/196 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910