DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9541 and Ak7

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001101525.2	Gene:	Ak7 / 314416	RGDID:	1309600	Length:	724	Species:	Rattus norvegicus

Alignment Length:	540	Identity:	91/540 - (16%)
Similarity:	178/540 - (32%)	Gaps:	160/540 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DTGEPGNDWNLTRN-----------RNGQNAGDLEAAAAAGRLGSTNVGAIDMQNAG---KIKFD 64
            ||...||......|           ...:...:.::|.||....:|.|.....|..|   |::..
  Rat    25 DTYSSGNIGKFLANCVAGASLEEIGEEEEEEDETKSAGAATEATTTKVKEGTFQIVGTLAKLEST 89

  Fly    65 PPKVPVIFVLGGPGS----GKVTHCDTFMQERRGVTHINMMDLLQQY--------AMGNDMQDFS 117
            .|...|.....|...    .::..||        |...|:.:..||.        |:..::..|.
  Rat    90 RPDFAVETYSHGTSREDLLARLLECD--------VVVYNITENAQQVQEALWAVSALSEEISHFE 146

  Fly   118 QLSSKTVTEVLMLEMKMAP-----AAKAYLISGYPR-----SMRDVVEYSEKIQVVNGVILISWR 172
            :.....:...:|...:..|     :...:....|.|     :.:|.:. :||:.:..|.....:.
  Rat   147 KRKMFILLSTVMTWARSKPLDPDDSEVPFTEEDYRRRKHHPNFQDHIN-AEKLVLKFGKNAKKFV 210

  Fly   173 QSVLQKQIDYGAKLGHVVLSLAKMELENFFK-------NVMPVADYFDQSDMLLAVNGERAPTEV 230
            ..|:...:.||.:.|         .|..|||       ..:||  :.|.|:.:.|::
  Rat   211 TYVVASGLQYGVEGG---------ILHAFFKMAWLGEIPALPV--FGDGSNCIPAIH-------- 256

  Fly   231 YKDFRTAVLDILSTLEN---QEAVMNGVTGMGRGIHDIPGSI--VSVDTAPSQAQQGTQIAEDND 290
                   |||:...::|   ....::.:..:...:|.:...:  :|.:|.|.:.|   ::.::|
  Rat   257 -------VLDLAGVIQNVIDHVPKLHYLVAVDESVHTLEDLVKCISKNTGPGKIQ---KVPKEN- 310

  Fly   291 VTNASETAGTVLARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAGP-----D 350
                     ..|.:||..|.:|    ..:..|:.......::..:....|....:..|.     .
  Rat   311 ---------AFLTKDLTQEHLD----QLLVNLRMEALFVKENFNIRWAAQTGFVENIGSILKEYK 362

  Fly   351 ESGSDLPPIIWVIGGPGSNKATL---CLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKE 412
            :|...||..|.::|.|...|:::   .:|...|:    ||.:..::           :|:.|..|
  Rat   363 QSRGLLPIKICILGPPAVGKSSISGELVKYYKLH----HIKIKDVI-----------SEAIAKLE 412

  Fly   413 ALAAGDMAPEK--------------------SLNQLLETNLRQLRDR-----------------T 440
            |:.|...:.|:                    .:.:.:|.|..:|.|:                 .
  Rat   413 AIVAPKESTEEEEGEEEEEEENVEDAQELLDGIKESMEQNAGRLEDQYVIRFVKEKLKSMPCKNQ 477

  Fly   441 GIIVDGYPRNLQQVKYFENK 460
            |.::||:|:...|.|...|:
  Rat   478 GYVLDGFPKTYDQAKDLFNQ 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427	31/199 (16%)
		ADK	70..230	CDD:238713	31/188 (16%)
		aden_kin_iso1	358..521	CDD:130427	25/143 (17%)
		ADK	359..521	CDD:238713	25/142 (18%)
Ak7	NP_001101525.2	WcaG	<149..299	CDD:223528	27/176 (15%)
		NADB_Rossmann	<195..300	CDD:304358	23/130 (18%)
		ADK	371..>549	CDD:238713	25/142 (18%)
		RILP-like	<615..693	CDD:304877
		Dpy-30	680..721	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342313
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930