DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and AK2

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001616.1	Gene:	AK2 / 204	HGNCID:	362	Length:	239	Species:	Homo sapiens

Alignment Length:	193	Identity:	38/193 - (19%)
Similarity:	76/193 - (39%)	Gaps:	62/193 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 VIGGPGSNKAT--------LCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAAGD 418
            ::|.||:.|.|        .|:         .|::.|.:||.:..|......:   :|..:.||.
Human    20 LLGPPGAGKGTQAPRLAENFCV---------CHLATGDMLRAMVASGSELGKK---LKATMDAGK 72

  Fly   419 MAPEKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQR------------PPIILL- 470
            :..::.:.:|:|.||.....:.|.::||:||.::|.:..::..::|            |..:|:
Human    73 LVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIR 137

  Fly   471 ----------------------------DCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLK 505
                                        |.:...|.| |.||...:.:.||:.:..||.|:::
Human   138 RITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIR-RSDDNEKALKIRLQAYHTQTTPLIE 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	38/193 (20%)
		ADK	359..521	CDD:238713	38/193 (20%)
AK2	NP_001616.1	ADK	20..204	CDD:395329	38/193 (20%)
		NMP. /evidence=ECO:0000255\|HAMAP-Rule:MF_03168, ECO:0000269\|Ref.17	45..74		7/31 (23%)
		LID. /evidence=ECO:0000255\|HAMAP-Rule:MF_03168, ECO:0000269\|Ref.17	141..178		4/37 (11%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..169		1/18 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910