DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and AK1

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001305051.1	Gene:	AK1 / 203	HGNCID:	361	Length:	210	Species:	Homo sapiens

Alignment Length:	183	Identity:	58/183 - (31%)
Similarity:	88/183 - (48%)	Gaps:	30/183 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 IIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAAGDMAPEK 423
            ||:|:|||||.|.|.|.|.| ...|:.|:|.|.|||:...|   .:.....:.|.:..|.:.|
Human    26 IIFVVGGPGSGKGTQCEKIV-QKYGYTHLSTGDLLRSEVSS---GSARGKKLSEIMEKGQLVP-- 84

  Fly   424 SLNQLLETNLRQLRD--------RTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSK------ 474
                 |||.|..|||        ..|.::|||||.:||.:.||.:..|...::.:|...
Human    85 -----LETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQR 144

  Fly   475 -LQLGR--GRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIV--DGDTDS 522
             |:.|.  ||:||...:.::|||.:.:.|.|::...:....::.|  :|..||
Human   145 LLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDS 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427
		ADK	70..230	CDD:238713
		aden_kin_iso1	358..521	CDD:130427	56/180 (31%)
		ADK	359..521	CDD:238713	56/180 (31%)
AK1	NP_001305051.1	aden_kin_iso1	22..209	CDD:130427	58/183 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920